Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 13/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | FPR2 | P25090 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29521416 | 0.85 | HDAC1 (0.64) | CNR1NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL21114827 | 0.85 | HDAC1 (0.64) | CNR1NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL23033247 | 0.85 | MEN1 (0.56) | CNR1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL23033249 | 0.84 | SMN1; SMN2 (0.51) | CNR1HTTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23033084 | 0.81 | IDO1 (0.49) | CNR1HTTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL23033398 | 0.80 | RHOC (0.56) | CNR1HTTKMT2AMEN1KDM4E | |
| SCHEMBL579606 | 0.80 | OPRM1 (0.65) | KMT2AMEN1NPSR1KDM4E | |
| SCHEMBL11922722 | 0.80 | SCN8A (0.57) | HTTNPC1RAB9ACA12CA1 | |
| SCHEMBL579570 | 0.79 | CYP1A2 (0.53) | CNR1HTTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL197282 | 0.79 | SMN1; SMN2 (0.67) | CNR1HTTNPC1RAB9ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210052519-A1 | Small molecule drugs and related methods for treatment of diseases related to tdo-43, alpha-synuclein, huntingtin's protein and tau protein oligomer formation | ACELOT,INC (US) | 2021-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210052519-A1 | Small molecule drugs and related methods for treatment of diseases related to tdo-43, alpha-synuclein, huntingtin's protein and tau protein oligomer formation | HTT, TARDBP, SNCA | CNR1 4185/4885HTT 1/4885FPR2 4519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.