Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23033513 | 0.82 | POLB (0.62) | HTTMAPTPOLBTSHRACLY | |
| SCHEMBL23033389 | 0.81 | BACE1 (0.43) | HTTMAPTPOLBGAAMEN1 | |
| SCHEMBL6354556 | 0.77 | ALDH1A1 (0.59) | HTTMAPTPOLBMEN1KMT2A | |
| SCHEMBL23033428 | 0.76 | ALDH1A1 (0.47) | MAPTPOLBMEN1KMT2ACYP1A2 | |
| SCHEMBL23033329 | 0.75 | ALDH1A1 (0.73) | HTTMAPTPOLBMEN1KMT2A | |
| SCHEMBL23033434 | 0.75 | POLB (0.48) | HTTMAPTPOLBGAAABL1 | |
| SCHEMBL23033426 | 0.75 | CYP1A2 (0.43) | HTTMAPTPOLBMEN1KMT2A | |
| SCHEMBL23033704 | 0.74 | CYP1A2 (0.58) | POLBMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL23033983 | 0.73 | NPC1 (0.52) | MAPTGAAMEN1KMT2ATSHR | |
| SCHEMBL23033323 | 0.71 | ALDH1A1 (0.55) | HTTMAPTPOLBGAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021032209-A1 | ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF | 四川海思科制药有限公司 | 2021-02-25 | — | — | WO | disclosed |