Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | ACLY | P53396 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23033434 | 0.86 | POLB (0.48) | POLBACLYHPGDSMN1; SMN2MALT1 | |
| SCHEMBL23033474 | 0.85 | POLB (0.55) | POLBKDM4EALDH1A1NAMPTLMNA | |
| SCHEMBL23033577 | 0.82 | HTT (0.49) | POLBACLYHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL23033389 | 0.81 | BACE1 (0.43) | POLBACLYHPGDSMN1; SMN2BACE1 | |
| SCHEMBL29619023 | 0.81 | POLB (0.64) | POLBHPGDSMN1; SMN2MALT1ACHE | |
| SCHEMBL22000031 | 0.81 | POLB (0.64) | POLBACLYHPGDSMN1; SMN2MALT1 | |
| SCHEMBL23033329 | 0.81 | ALDH1A1 (0.73) | POLBHPGDSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL6354556 | 0.80 | ALDH1A1 (0.59) | POLBSMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL29130900 | 0.78 | POLB (0.64) | POLBHPGDSMN1; SMN2MALT1ACHE | |
| SCHEMBL8901878 | 0.77 | POLB (0.62) | POLBHPGDSMN1; SMN2MALT1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021032209-A1 | ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF | 四川海思科制药有限公司 | 2021-02-25 | — | — | WO | disclosed |