Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ACLY | P53396 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23033513 | 0.86 | POLB (0.62) | POLBALDH1A1HPGDACLYMAPT | |
| SCHEMBL23033329 | 0.79 | ALDH1A1 (0.73) | POLBALDH1A1HPGDMAPTLMNA | |
| SCHEMBL23033577 | 0.75 | HTT (0.49) | POLBALDH1A1HPGDACLYMAPT | |
| SCHEMBL19550575 | 0.75 | ITGB1 (0.50) | POLBALDH1A1HPGDKDM4EPIP5K1C | |
| SCHEMBL19550572 | 0.75 | ITGB1 (0.50) | POLBALDH1A1HPGDKDM4EPIP5K1C | |
| SCHEMBL19551054 | 0.75 | ITGB1 (0.50) | POLBALDH1A1HPGDKDM4EPIP5K1C | |
| SCHEMBL23033389 | 0.74 | BACE1 (0.43) | POLBALDH1A1HPGDACLYMAPT | |
| SCHEMBL25668524 | 0.74 | NAMPT (0.53) | POLBALDH1A1MAPTKDM4EPIP5K1C | |
| SCHEMBL6354556 | 0.73 | ALDH1A1 (0.59) | POLBALDH1A1MAPTHTTKDM4E | |
| SCHEMBL23033474 | 0.73 | POLB (0.55) | POLBALDH1A1MAPTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021032209-A1 | ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF | 四川海思科制药有限公司 | 2021-02-25 | — | — | WO | disclosed |