Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANXA2 | P07355 | 5/20 | 0.66 |
| ▸ | S100A10 | P60903 | 5/20 | 0.66 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 4/20 | 0.44 |
| ▸ | CCR2 | P41597 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2232974 | 0.84 | ANXA2 (0.65) | ANXA2S100A10MALT1ALDH1A1 | |
| SCHEMBL2235370 | 0.82 | ANXA2 (0.53) | ANXA2S100A10MALT1CCR1CCR2 | |
| SCHEMBL2234193 | 0.82 | ANXA2 (0.67) | ANXA2S100A10MALT1KDM4ERXFP1 | |
| SCHEMBL2233839 | 0.80 | ANXA2 (0.68) | ANXA2S100A10KDM4ERXFP1TDP1 | |
| SCHEMBL12943493 | 0.77 | RXFP1 (0.63) | ANXA2S100A10CCR1CCR2KDM4E | |
| SCHEMBL2232358 | 0.77 | CCR1 (0.59) | ANXA2S100A10CCR1CCR2KDM4E | |
| SCHEMBL12668752 | 0.76 | PPARG (0.57) | KDM4ERXFP1ALDH1A1ALOX15TSHR | |
| SCHEMBL2234993 | 0.76 | ANXA2 (0.65) | ANXA2S100A10CCR1CCR2KDM4E | |
| SCHEMBL2304628 | 0.75 | ANXA2 (0.67) | ANXA2S100A10CCR1CCR2KDM4E | |
| SCHEMBL2231482 | 0.75 | ANXA2 (0.58) | ANXA2S100A10CCR1CCR2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092505-A1 | S100 PROTEIN BINDING INTERACTION INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2011-08-04 | — | — | WO | disclosed |