Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANXA2 | P07355 | 5/20 | 0.67 |
| ▸ | S100A10 | P60903 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | FPR1 | P21462 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2233839 | 0.94 | ANXA2 (0.68) | ANXA2S100A10ALDH1A1KDM4EHPGD | |
| SCHEMBL2232974 | 0.84 | ANXA2 (0.65) | ANXA2S100A10ALDH1A1MALT1 | |
| SCHEMBL681885 | 0.82 | ALDH1A1 (0.53) | ANXA2S100A10ALDH1A1KDM4EHPGD | |
| SCHEMBL2303389 | 0.82 | ANXA2 (0.66) | ANXA2S100A10ALDH1A1KDM4ETDP1 | |
| SCHEMBL2235370 | 0.81 | ANXA2 (0.53) | ANXA2S100A10ALDH1A1KDM4ETDP1 | |
| SCHEMBL12668752 | 0.79 | PPARG (0.57) | ALDH1A1KDM4EMAPTALOX15RXFP1 | |
| SCHEMBL2236184 | 0.77 | ANXA2 (0.55) | ANXA2S100A10HPGDTDP1CYP2C9 | |
| SCHEMBL2232358 | 0.76 | CCR1 (0.59) | ANXA2S100A10ALDH1A1KDM4EHPGD | |
| SCHEMBL13927439 | 0.75 | ALDH1A1 (0.52) | ANXA2S100A10ALDH1A1KDM4EHPGD | |
| SCHEMBL2234993 | 0.75 | ANXA2 (0.65) | ANXA2S100A10ALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092505-A1 | S100 PROTEIN BINDING INTERACTION INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2011-08-04 | — | — | WO | claimed |
| WO-2011092505-A1 | S100 PROTEIN BINDING INTERACTION INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2011-08-04 | — | — | WO | disclosed |