Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.70 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.70 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.70 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.70 |
| ▸ | RAB9A | P51151 | 11/20 | 0.70 |
| ▸ | NPC1 | O15118 | 10/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | UTRN | P46939 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29479597 | 0.91 | NPC1 (0.70) | CASP3SENP7SENP8SENP6RAB9A | |
| SCHEMBL23012175 | 0.91 | NPC1 (0.70) | CASP3SENP7SENP8SENP6RAB9A | |
| SCHEMBL23033557 | 0.85 | CASP3 (0.51) | CASP3SENP7SENP8SENP6RAB9A | |
| SCHEMBL23012327 | 0.82 | CASP3 (0.47) | CASP3SENP7SENP8SENP6RAB9A | |
| SCHEMBL29479685 | 0.81 | LMNA (0.46) | CASP3SENP7SENP8SENP6RAB9A | |
| SCHEMBL28713359 | 0.81 | LMNA (0.46) | CASP3SENP7SENP8SENP6RAB9A | |
| SCHEMBL23034143 | 0.80 | MAPT (0.71) | CASP3SENP7SENP8SENP6RAB9A | |
| SCHEMBL31165944 | 0.79 | KDM4E (0.67) | CASP3SENP7SENP8SENP6RAB9A | |
| SCHEMBL28701684 | 0.79 | ALDH1A1 (0.71) | CASP3SENP7RAB9ANPC1KMT2A | |
| SCHEMBL23033530 | 0.77 | ALDH1A1 (0.52) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021032209-A1 | ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF | 四川海思科制药有限公司 | 2021-02-25 | — | — | WO | disclosed |