Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.67 |
| ▸ | RAB9A | P51151 | 9/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | POLB | P06746 | 4/20 | 0.67 |
| ▸ | UTRN | P46939 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.61 |
| ▸ | HPGD | P15428 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.61 |
| ▸ | RELA | Q04206 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | CASP3 | P42574 | 3/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23012175 | 0.86 | NPC1 (0.70) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL29479597 | 0.86 | NPC1 (0.70) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL23034143 | 0.84 | MAPT (0.71) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL4082942 | 0.84 | ALDH1A1 (0.79) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL2244809 | 0.82 | NPC1 (0.85) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL1675430 | 0.81 | UTRN (0.68) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL23012658 | 0.81 | LMNA (0.46) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL2243174 | 0.80 | NPC1 (1.00) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28935979 | 0.79 | MAPT (0.58) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL2245124 | 0.79 | UTRN (1.00) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269725-A | Anti-influenza virus compound and preparation method and application thereof | 四川海思科制药有限公司 | 2022-04-01 | — | — | CN | disclosed |
| WO-2021032209-A1 | ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF | 四川海思科制药有限公司 | 2021-02-25 | — | — | WO | disclosed |