Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL231331 | 0.92 | THRB (0.57) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL1781744 | 0.85 | THRB (0.49) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL1780823 | 0.82 | TDP1 (0.46) | THRBTSHRALDH1A1TDP1KDM4E | |
| SCHEMBL5835079 | 0.82 | TSHR (0.57) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL3358609 | 0.81 | THRB (0.54) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL3356443 | 0.81 | THRB (0.54) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL8899006 | 0.77 | THRB (0.56) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL230344 | 0.77 | THRB (0.56) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL230731 | 0.77 | THRB (0.56) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL69211 | 0.77 | THRB (0.84) | THRBTSHRHPGDALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8247590-B2 | Method for preventing polymerization of unsaturated organosilicon compounds | WACKER CHEMIE AG (DE) | 2012-08-21 | — | — | US | disclosed |
| US-20120004437-A1 | METHOD FOR PRODUCING (METH)ACRYLOSILANES | WACKER CHEMIE AG (DE) | 2012-01-05 | — | — | US | disclosed |
| US-20110118493-A1 | METHOD FOR PREVENTING POLYMERIZATION OF UNSATURATED ORGANOSILICON COMPOUNDS | WACKER CHEMIE AG (DE) | 2011-05-19 | — | — | US | disclosed |