Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3358609 | 0.97 | THRB (0.54) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL231329 | 0.92 | THRB (0.59) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL230344 | 0.84 | THRB (0.56) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL230731 | 0.84 | THRB (0.56) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL8899006 | 0.84 | THRB (0.56) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL8899017 | 0.83 | THRB (0.59) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL229251 | 0.83 | THRB (0.51) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL2168203 | 0.82 | THRB (0.54) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL1063223 | 0.82 | THRB (0.54) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL71730 | 0.81 | TSHR (0.59) | THRBTSHRHPGDALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100010166-A1 | SILANE-TERMINATED PREPOLYMERS AND RELATIVE ADHESIVE SEALANT FORMULATIONS | N.P.T. S.R.L. (IT) | 2010-01-14 | — | — | US | disclosed |
| EP-2064256-A1 | SILANE-TERMINATED PREPOLYMERS AND RELATIVE ADHESIVE SEALANT FORMULATIONS | N.P.T. S.R.L. (IT) | 2009-06-03 | — | — | EP | disclosed |
| WO-2008031895-A1 | SILANE-TERMINATED PREPOLYMERS AND RELATIVE ADHESIVE SEALANT FORMULATIONS | N.P.T. S.R.L. (IT) | 2008-03-20 | — | — | WO | disclosed |