Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.49 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 7/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | PDE6D | O43924 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1784170 | 0.91 | THRB (0.54) | THRBTGM2TSHRALDH1A1GAA | |
| SCHEMBL230345 | 0.85 | THRB (0.52) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL230456 | 0.81 | ELANE (0.38) | THRBTSHRALDH1A1POLB | |
| SCHEMBL229251 | 0.77 | THRB (0.51) | THRBTGM2TSHRALDH1A1TP53 | |
| SCHEMBL28648452 | 0.77 | THRB (0.44) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL231331 | 0.76 | THRB (0.57) | THRBTGM2TSHRALDH1A1GAA | |
| SCHEMBL27863619 | 0.76 | THRB (0.43) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL1642965 | 0.74 | THRB (0.72) | THRBTGM2TSHRALDH1A1GAA | |
| SCHEMBL2582629 | 0.74 | THRB (0.49) | THRBTGM2ALDH1A1GAATP53 | |
| SCHEMBL229250 | 0.74 | THRB (0.54) | THRBTGM2TSHRALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8247590-B2 | Method for preventing polymerization of unsaturated organosilicon compounds | WACKER CHEMIE AG (DE) | 2012-08-21 | — | — | US | disclosed |
| US-20110118493-A1 | METHOD FOR PREVENTING POLYMERIZATION OF UNSATURATED ORGANOSILICON COMPOUNDS | WACKER CHEMIE AG (DE) | 2011-05-19 | — | — | US | disclosed |