Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2303447 | 1.00 | ALDH1A1 (0.42) | ALDH1A1MAPTPIK3CAMTORPTGS2 | |
| SCHEMBL2240681 | 0.81 | MAPT (0.42) | ALDH1A1MAPTGAASMN1; SMN2RAB9A | |
| SCHEMBL2240673 | 0.81 | MAPT (0.42) | ALDH1A1MAPTGAASMN1; SMN2RAB9A | |
| SCHEMBL2996618 | 0.79 | SMN1; SMN2 (0.38) | ALDH1A1MAPTGAASMN1; SMN2RAB9A | |
| SCHEMBL2992544 | 0.78 | SMN1; SMN2 (0.39) | ALDH1A1MAPTGAASMN1; SMN2RAB9A | |
| SCHEMBL2990855 | 0.76 | ALDH1A1 (0.36) | ALDH1A1MAPTGAASMN1; SMN2HTR6 | |
| SCHEMBL2244188 | 0.75 | SMN1; SMN2 (0.37) | ALDH1A1MAPTGAASMN1; SMN2RAB9A | |
| SCHEMBL2244181 | 0.75 | SMN1; SMN2 (0.37) | ALDH1A1MAPTGAASMN1; SMN2RAB9A | |
| SCHEMBL2998009 | 0.75 | SMN1; SMN2 (0.36) | ALDH1A1MAPTGAASMN1; SMN2RAB9A | |
| SCHEMBL12346964 | 0.75 | HTR6 (0.49) | ALDH1A1PIK3CAMTORSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110201599-A1 | CDK Modulators | EXELIXIS, INC. (US) | 2011-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201599-A1 | CDK Modulators | CDK3, CDK1, CDKL1 | ALDH1A1 2581/4885MAPT 2120/4885PIK3CA 371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.