SCHEMBL2303569

SCHEMBL2303569

COc1ccc(N)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 1.00
MEN1 O00255 6/20 1.00
KMT2A Q03164 6/20 1.00
RAB9A P51151 6/20 1.00
ALDH1A1 P00352 5/20 1.00
ADORA2A P29274 5/20 1.00
SMN1; SMN2 Q16637 5/20 1.00
POLB P06746 4/20 1.00
MAPK1 P28482 3/20 1.00
NPSR1 Q6W5P4 2/20 1.00
FGB P02675 1/20 1.00
THRB P10828 1/20 1.00
PPARG P37231 1/20 1.00
NCOA2 Q15596 1/20 1.00
NCOA1 Q15788 1/20 1.00
TDP1 Q9NUW8 3/20 0.79
KDM4E B2RXH2 3/20 0.79
USP2 O75604 2/20 0.79
DUSP3 P51452 1/20 0.79
CSNK1A1 P48729 2/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,4-Dimethoxyanthraquinone SCHEMBL3417221 0.89 MAPT (1.00) MAPTMEN1KMT2ARAB9AALDH1A1
SCHEMBL498666 0.88 MEN1 (0.79) MAPTMEN1KMT2ARAB9AALDH1A1
SCHEMBL11243983 0.87 ALDH1A1 (0.76) MAPTMEN1KMT2ARAB9AALDH1A1
SCHEMBL498594 0.87 ALDH1A1 (0.76) MAPTMEN1KMT2ARAB9AALDH1A1
SCHEMBL498449 0.87 ALDH1A1 (0.76) MAPTMEN1KMT2ARAB9AALDH1A1
SCHEMBL11580900 0.84 MAPT (0.72) MAPTMEN1KMT2ARAB9AALDH1A1
SCHEMBL6901121 0.84 MAPT (0.81) MAPTMEN1KMT2ARAB9AALDH1A1
SCHEMBL525762 0.82 ADORA2A (1.00) MAPTMEN1KMT2ARAB9AALDH1A1
SCHEMBL29361319 0.82 ADORA2A (1.00) MAPTMEN1KMT2ARAB9AALDH1A1
SCHEMBL10809856 0.81 MEN1 (0.68) MAPTMEN1KMT2ARAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0525073-A1 ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA. DU PONT (US) 1993-02-03 EP claimed
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed
CN-116194805-B Colored contact lens 库博光学国际有限公司 2025-01-10 CN disclosed
US-12164182-B2 Contact lens COOPERVISION INTERNATIONAL LIMITED (GB) 2024-12-10 US disclosed
EP-4172667-B1 COLOURED CONTACT LENS COOPERVISION INT LTD (GB) 2023-12-13 EP disclosed
CN-116194805-A9 Colored contact lens 库博光学国际有限公司 2023-07-21 CN disclosed
CN-116194805-A Colored contact lens 库博光学国际有限公司 2023-05-30 CN disclosed
EP-4172667-A1 COLOURED CONTACT LENS CooperVision International Limited (GB) 2023-05-03 EP disclosed
WO-2022053791-A1 COLOURED CONTACT LENS COOPERVISION INTERNATIONAL LIMITED (GB) 2022-03-17 WO disclosed
US-20220075210-A1 CONTACT LENS COOPERVISION INTERNATIONAL LIMITED (GB) 2022-03-10 US disclosed
US-8778876-B2 Small-molecule inhibitors of Dengue and West Nile virus proteases THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2014-07-15 US disclosed
US-4146535-A Azo dyes having a 3-cyano- or 3-carbamoyl-2,6-diamino-pyridine coupling component BASF AKTIENGESELLSCHAFT (DE) 1979-03-27 US disclosed
US-4083684-A AZO DYES, WASHFASTNESS, PHOTOSTABILITY, SOLVENT RESISTANCE BASF AKTIENGESELLSCHAFT (DT) 1978-04-11 US disclosed
US-4082778-A ANTHRAQUINONE DYES, ORGANIC PIGMENTS CIBA-GEIGY CORPORATION (US) 1978-04-04 US disclosed
US-4076713-A Indanthrene dyes PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1978-02-28 US disclosed
US-3972881-A VAT, CELLULOSE CIBA-GEIGY CORPORATION (US) 1976-08-03 US disclosed
US-3969302-A Process for the dyeing of colored shaped articles of high polymer, synthetic resins and preparations for such process CIBA-GEIGY AG (CH) 1976-07-13 US disclosed
US-3964862-A Process for dyeing and printing textile materials of synthetic organic fibers CIBA-GEIGY AG (CH) 1976-06-22 US disclosed
US-3939113-A ANTHRAQUINONE DYES CIBA-GEIGY CORPORATION (US) 1976-02-17 US disclosed
US-3935208-A NATURAL OR REGENERATED CELLULOSE ALTERMATT HANS 1976-01-27 US disclosed