SCHEMBL11243983

SCHEMBL11243983

COc1ccc(OC)c2c1C(=O)c1c(N)ccc(N)c1C2=O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.76
MAPT P10636 5/20 0.76
THRB P10828 3/20 0.76
MEN1 O00255 3/20 0.76
KMT2A Q03164 3/20 0.76
MAPK1 P28482 2/20 0.76
RAB9A P51151 2/20 0.76
NPSR1 Q6W5P4 2/20 0.76
ADORA2A P29274 2/20 0.76
FGB P02675 1/20 0.76
POLB P06746 1/20 0.76
PPARG P37231 1/20 0.76
NCOA2 Q15596 1/20 0.76
NCOA1 Q15788 1/20 0.76
SMN1; SMN2 Q16637 1/20 0.76
KDM4E B2RXH2 3/20 0.57
HTT P42858 2/20 0.57
S1PR4 O95977 1/20 0.57
HSP90AA1 P07900 1/20 0.57
G6PD P11413 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL498594 1.00 ALDH1A1 (0.76) ALDH1A1MAPTTHRBMEN1KMT2A
SCHEMBL498449 1.00 ALDH1A1 (0.76) ALDH1A1MAPTTHRBMEN1KMT2A
SCHEMBL2303569 0.87 MAPT (1.00) ALDH1A1MAPTTHRBMEN1KMT2A
SCHEMBL498666 0.86 MEN1 (0.79) ALDH1A1MAPTTHRBMEN1KMT2A
SCHEMBL11134106 0.86 MAPT (0.73) ALDH1A1MAPTTHRBMEN1KMT2A
SCHEMBL11690019 0.80 MAPT (0.59) ALDH1A1MAPTTHRBMEN1KMT2A
SCHEMBL11246302 0.79 ALDH1A1 (0.66) ALDH1A1MAPTTHRBMEN1KMT2A
SCHEMBL3909101 0.79 MAPT (0.64) ALDH1A1MAPTTHRBMEN1KMT2A
SCHEMBL29390741 0.78 THRB (1.00) ALDH1A1MAPTTHRBMEN1KMT2A
SCHEMBL125495 0.78 THRB (1.00) ALDH1A1MAPTTHRBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0025926-B1 PROCESS FOR THE PREPARATION OF MONOAROYLATED 1,4-DIAMINO ANTHRAQUINONES BAYER AG (DE) 1982-11-24 EP disclosed
US-4324732-A IN PRESENCE OF TERITIARY ALIPHATIC AMINOALCOHOL AND/OR QUARTERNARY AMMONIUM COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1982-04-13 US disclosed
EP-0025926-A1 Process for the preparation of monoaroylated 1,4-diamino anthraquinones BAYER AG (DE) 1981-04-01 EP disclosed