Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21491177 | 0.90 | MAPT (0.40) | MAPTSMN1; SMN2ALDH1A1HTTL3MBTL1 | |
| SCHEMBL23036779 | 0.85 | GAA (0.36) | MAPTSMN1; SMN2ALDH1A1HTTHRH3 | |
| SCHEMBL31472404 | 0.83 | TSHR (0.40) | MAPTSMN1; SMN2ALDH1A1HTTKMT2A | |
| SCHEMBL21491244 | 0.83 | TSHR (0.40) | MAPTSMN1; SMN2ALDH1A1HTTKMT2A | |
| SCHEMBL21491154 | 0.83 | OPRK1 (0.37) | KMT2AHRH3 | |
| SCHEMBL25332741 | 0.82 | MAPT (0.44) | MAPTSMN1; SMN2ALDH1A1HTTL3MBTL1 | |
| SCHEMBL21491341 | 0.81 | MAPT (0.41) | MAPTSMN1; SMN2ALDH1A1HTTKMT2A | |
| SCHEMBL21491227 | 0.81 | ATAD2 (0.44) | MAPTALDH1A1HTTL3MBTL1KMT2A | |
| SCHEMBL23036725 | 0.80 | KCNK3 (0.32) | L3MBTL1 | |
| SCHEMBL23036717 | 0.79 | BACE1 (0.31) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3784666-A1 | ANTIPROLIFERATION COMPOUNDS AND USES THEREOF | Merck Patent GmbH (DE) | 2021-03-03 | — | — | EP | disclosed |