Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21491177 | 0.93 | MAPT (0.40) | MAPTALDH1A1HTTBACE1PKM | |
| SCHEMBL25331015 | 0.85 | KDM1A (0.38) | MAPTALDH1A1HTTBACE1RAB9A | |
| SCHEMBL25331369 | 0.85 | POLB (0.41) | MAPTALDH1A1HTTBACE1GAA | |
| SCHEMBL25333214 | 0.83 | NR1H2 (0.41) | MAPTALDH1A1HTTNPSR1SMN1; SMN2 | |
| SCHEMBL23036751 | 0.82 | MAPT (0.38) | MAPTALDH1A1HTTBACE1L3MBTL1 | |
| SCHEMBL25334663 | 0.81 | KDM1A (0.42) | MAPTALDH1A1HTTBACE1GAA | |
| SCHEMBL21491243 | 0.78 | OPRK1 (0.35) | CYP2C9CYP2C19KMT2A | |
| SCHEMBL25332686 | 0.78 | LIPG (0.34) | BACE1 | |
| SCHEMBL23036739 | 0.78 | MAPT (0.39) | MAPTALDH1A1HTTL3MBTL1NPSR1 | |
| SCHEMBL21491127 | 0.77 | OPRK1 (0.35) | MAPTHTTCYP2C9CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139241-A1 | HETEROCYCLIC COMPOUNDS AS UBIQUITIN SPECIFIC PROTEASE 7 INHIBITORS | ALMAC DISCOVERY LIMITED (GB) | 2023-07-27 | — | — | WO | disclosed |