SCHEMBL23040363

SCHEMBL23040363

CC1(C)c2ccccc2-c2cc(Br)c(Nc3ccccc3)cc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 6/20 0.37
▸ KMT2A Q03164 6/20 0.37
▸ MAPT P10636 5/20 0.37
▸ ALDH1A1 P00352 4/20 0.37
▸ KDM4E B2RXH2 4/20 0.37
▸ TDP1 Q9NUW8 3/20 0.37
▸ EGFR P00533 3/20 0.37
▸ SRC P12931 3/20 0.37
▸ SMN1; SMN2 Q16637 3/20 0.37
▸ LMNA P02545 3/20 0.37
▸ GLA P06280 2/20 0.37
▸ HPGD P15428 2/20 0.37
▸ RGS12 O14924 1/20 0.37
▸ GMNN O75496 1/20 0.37
▸ PRKD3 O94806 1/20 0.37
▸ PRKCG P05129 1/20 0.37
▸ PRKCB P05771 1/20 0.37
▸ CYP3A4 P08684 1/20 0.37
▸ PRKCA P17252 1/20 0.37
▸ NFKB1 P19838 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30714373 1.00 MEN1 (0.37) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL26924733 0.92 PTGER4 (0.36) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL26408602 0.87 KDR (0.33) ALDH1A1NFKB1PDK2NPC1RAB9A
SCHEMBL30683251 0.85 MAPT (0.39) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL23040346 0.84 GAA (0.42) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL26660392 0.82 MAPT (0.37) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL30612824 0.82 MAPT (0.37) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL30714362 0.81 MEN1 (0.42) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL10044314 0.81 GAA (0.42) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL18525761 0.80 PDK2 (0.36) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11937499-B2 Aromatic amine derivative and organic electroluminescent devices containing the same Beijing Summer Sprout Technology Co., Ltd. (CN) 2024-03-19 — — US disclosed
WO-2023239091-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2023-12-14 — — WO disclosed
CN-112430190-B Aromatic amine derivative and organic electroluminescent device comprising same 北京夏禾科技有限公司 2023-04-18 — — CN disclosed
US-20210066595-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICES CONTAINING THE SAME Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-03-04 — — US disclosed
CN-112430190-A Aromatic amine derivative and organic electroluminescent device comprising same 北京夏禾科技有限公司 2021-03-02 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210066595-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICES CONTAINING THE SAME TYR, DDC, AOC2 MEN1 3099/4885KMT2A 102/4885MAPT 276/4885
US-11937499-B2 Aromatic amine derivative and organic electroluminescent devices containing the same TYR, DDC, AOC2 MEN1 3099/4885KMT2A 102/4885MAPT 276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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