SCHEMBL23040932

SCHEMBL23040932

CCC(CC)(NC(=O)OCc1ccccc1)C(=O)NCCN(C)C

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.45
LMNA P02545 1/20 0.45
CTSS P25774 2/20 0.43
HTT P42858 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
MAPT P10636 1/20 0.43
CTSL P07711 1/20 0.42
CTSB P07858 1/20 0.42
CTSK P43235 1/20 0.42
ALOX5 P09917 1/20 0.42
TGM2 P21980 1/20 0.41
SYK P43405 1/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
UTS2R Q9UKP6 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17371252 0.85 MEN1 (0.49) MEN1KMT2ASMN1; SMN2LMNACTSS
SCHEMBL14772158 0.82 LMNA (0.65) MEN1KMT2ASMN1; SMN2LMNACTSS
SCHEMBL8981259 0.79 MEN1 (0.55) MEN1KMT2ASMN1; SMN2LMNACTSS
SCHEMBL22729336 0.79 MEN1 (0.47) MEN1KMT2ASMN1; SMN2LMNACTSS
SCHEMBL21222698 0.79 HTT (0.49) MEN1KMT2ASMN1; SMN2LMNACTSS
SCHEMBL16068102 0.77 MEN1 (0.63) MEN1KMT2ASMN1; SMN2LMNACTSS
SCHEMBL22729341 0.76 CTSS (0.46) MEN1KMT2ASMN1; SMN2LMNACTSS
SCHEMBL21227021 0.75 HTT (0.57) MEN1KMT2ASMN1; SMN2LMNACTSS
SCHEMBL2188218 0.75 SMN1; SMN2 (0.50) MEN1KMT2ASMN1; SMN2LMNACTSS
SCHEMBL17350365 0.74 HTT (0.67) SMN1; SMN2LMNACTSSHTTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110066302-B Glucopyranosyl derivative and use thereof 广东东阳光药业有限公司 2022-12-27 CN disclosed
US-11084842-B2 Glucopyranosyl derivative and use thereof SUNSHINE LAKE PHARMA CO., LTD. (CN) 2021-08-10 US disclosed
US-20210061839-A1 GLUCOPYRANOSYL DERIVATIVE AND USE THEREOF SUNSHINE LAKE PHARMA CO., LTD. (CN) 2021-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210061839-A1 GLUCOPYRANOSYL DERIVATIVE AND USE THEREOF SLC5A1, SLC5A2, UGGT1 MEN1 3921/4885KMT2A 2821/4885SMN1; SMN2 3631/4885
US-11084842-B2 Glucopyranosyl derivative and use thereof SLC5A1, SLC5A2, UGGT1 MEN1 3921/4885KMT2A 2821/4885SMN1; SMN2 3631/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.