Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | EPM2A | O95278 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPRG | P23470 | 1/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
| ▸ | PTPN9 | P43378 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28716842 | 0.91 | MAOB (0.41) | MAOBAOC3ADORA1KIF11NISCH | |
| SCHEMBL23041015 | 0.89 | KIF11 (0.41) | MAOBAOC3ADORA1KIF11NISCH | |
| SCHEMBL23041021 | 0.80 | MAOB (0.36) | MAOBAOC3ACACBKIF11NISCH | |
| SCHEMBL28659226 | 0.78 | ACACB (0.50) | MAOBAOC3ACACBAPPKIF11 | |
| SCHEMBL2232071 | 0.77 | APP (0.57) | MAOBAOC3ACACBAPPFFAR1 | |
| SCHEMBL24180475 | 0.72 | DHODH (0.49) | ADORA1KIF11KCNH2SCN10A | |
| SCHEMBL403812 | 0.71 | APP (0.50) | MAOBAOC3ACACBAPPKIF11 | |
| SCHEMBL28720093 | 0.71 | MAPT (0.36) | MAOBAOC3ADORA1KIF11NISCH | |
| SCHEMBL23042011 | 0.70 | KIF11 (0.37) | MAOBAOC3KIF11NISCHSCN5A | |
| SCHEMBL23510891 | 0.70 | SCN5A (0.37) | MAOBAOC3ACACBADORA1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4022007-B1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2024-04-03 | — | — | EP | disclosed |
| US-11739265-B2 | Aromatic isothiocyanates | MERCK PATENT GMBH (DE) | 2023-08-29 | — | — | US | disclosed |
| US-11739265-B2 | Aromatic isothiocyanates | MERCK PATENT GMBH (DE) | 2023-08-29 | — | — | US | disclosed |
| US-20220306938-A1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2022-09-29 | — | — | US | disclosed |
| EP-4022007-A1 | AROMATIC ISOTHIOCYANATES | Merck Patent GmbH (DE) | 2022-07-06 | — | — | EP | disclosed |
| CN-114302872-A | Aromatic isothiocyanates | 默克专利股份有限公司 | 2022-04-08 | — | — | CN | disclosed |
| WO-2021037962-A1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2021-03-04 | — | — | WO | disclosed |
| WO-2021037962-A1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2021-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220306938-A1 | AROMATIC ISOTHIOCYANATES | TRPA1, CRY1, FOXM1 | MAOB 2493/4885AOC3 1464/4885ACACB 1870/4885 |
| US-11739265-B2 | Aromatic isothiocyanates | TRPA1, CRY1, FOXM1 | MAOB 2493/4885AOC3 1464/4885ACACB 1870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.