Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23041367 | 0.84 | OPRK1 (0.52) | SLC6A9OPRK1OPRD1TSHRHTR1A | |
| SCHEMBL25311909 | 0.82 | OPRL1 (0.42) | SLC6A9OPRK1OPRL1OPRM1OPRD1 | |
| SCHEMBL1555927 | 0.79 | SLC6A9 (0.50) | SLC6A9OPRK1OPRL1OPRM1OPRD1 | |
| SCHEMBL17140600 | 0.77 | CCR5 (0.45) | OPRK1OPRL1OPRM1OPRD1CYP2D6 | |
| SCHEMBL9949023 | 0.77 | OPRL1 (0.58) | OPRK1OPRL1OPRM1OPRD1CYP2D6 | |
| SCHEMBL19851208 | 0.76 | OPRL1 (0.45) | SLC6A9OPRK1OPRL1OPRM1OPRD1 | |
| SCHEMBL25875253 | 0.76 | CYP2D6 (0.46) | SLC6A9OPRK1OPRL1OPRM1OPRD1 | |
| SCHEMBL21104902 | 0.76 | CYP2D6 (0.46) | SLC6A9OPRK1OPRL1OPRM1OPRD1 | |
| SCHEMBL25875252 | 0.76 | CYP2D6 (0.46) | SLC6A9OPRK1OPRL1OPRM1OPRD1 | |
| SCHEMBL25310611 | 0.75 | CRBN (0.40) | SLC6A9OPRK1OPRL1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021038419-A1 | KINASE INHIBITORS AND METHODS OF SYNTHESIS AND TREATMENT | INSILICO MEDICINE IP LIMITED (CN) | 2021-03-04 | — | — | WO | disclosed |