Methane

Methane

SCHEMBL2304232

C.O=C(O)C1=CCN2C=CC=CC2=C1

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2301142 0.98
Hydrochloric Acid SCHEMBL7615191 0.97
SCHEMBL27740707 0.97
SCHEMBL3971398 0.97
SCHEMBL27740660 0.91
SCHEMBL2299291 0.90
Toluene SCHEMBL27771933 0.87
SCHEMBL27771935 0.84 SMN1; SMN2 (0.40)
Hydrochloric Acid SCHEMBL7406597 0.82
SCHEMBL2304228 0.80 LMNA (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2536408-A1 EFFLUX PUMP INHIBITORS Wockhardt Research Centre (IN) 2012-12-26 EP claimed
WO-2011101710-A1 EFFLUX PUMP INHIBITORS WOCKHARDT RESEARCH CENTRE (IN) 2011-08-25 WO claimed
EP-2536408-A1 EFFLUX PUMP INHIBITORS Wockhardt Research Centre (IN) 2012-12-26 EP disclosed
WO-2011101710-A1 EFFLUX PUMP INHIBITORS WOCKHARDT RESEARCH CENTRE (IN) 2011-08-25 WO disclosed