⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2301142 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL7615191 | 0.97 | — | — | |
| SCHEMBL27740707 | 0.97 | — | — | |
| Methane SCHEMBL2304232 | 0.97 | — | — | |
| SCHEMBL27740660 | 0.91 | — | — | |
| SCHEMBL2299291 | 0.90 | — | — | |
| Toluene SCHEMBL27771933 | 0.87 | — | — | |
| SCHEMBL27771935 | 0.84 | SMN1; SMN2 (0.40) | — | |
| SCHEMBL2304228 | 0.80 | LMNA (0.30) | — | |
| SCHEMBL27751159 | 0.76 | DDX3X (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1175217-B8 | (S)-BENZOQUINOLIZINE CARBOXYLIC ACIDS AND THEIR USE AS ANTIBACTERIAL AGENTS | WOCKHARDT LTD (IN) | 2009-03-18 | — | — | EP | disclosed |
| EP-2030620-A1 | (s)-benzoquinolizine carboxylic acids and their use as antibacterial agents | Wockhardt Limited (IN) | 2009-03-04 | — | — | EP | disclosed |
| EP-1175217-B1 | (S)-BENZOQUINOLIZINE CARBOXYLIC ACIDS AND THEIR USE AS ANTIBACTERIAL AGENTS | WOCKHARDT LTD (IN) | 2008-12-03 | — | — | EP | disclosed |
| US-7247642-B2 | Antibacterial optically pure benzoquinolizine carboxylic acids, processes, compositions and methods of treatment | WOCKHARDT LIMITED (IN) | 2007-07-24 | — | — | US | disclosed |
| US-20030207908-A1 | Antibacterial optically pure benzoquinolizine carboxylic acids, processes, compositions and methods of treatment | WOCKHARDT LIMITED (IN) | 2003-11-06 | — | — | US | disclosed |
| EP-1175217-A2 | (S)-BENZOQUINOLIZINE CARBOXYLIC ACIDS AND THEIR USE AS ANTIBACTERIAL AGENTS | Wockhardt Limited (IN) | 2002-01-30 | — | — | EP | disclosed |
| WO-2000068229-A2 | (S)-BENZOQUINOLIZINE CARBOXYLIC ACIDS AND THEIR USE AS ANTIBACTERIAL AGENTS | WOCKHARDT LIMITED (IN) | 2000-11-16 | — | — | WO | disclosed |