Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2308470 | 0.87 | SLC1A2 (0.34) | SLC1A2 | |
| SCHEMBL7368083 | 0.86 | GRM4 (0.31) | — | |
| SCHEMBL7014956 | 0.79 | MAPT (0.41) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL4078899 | 0.77 | — | — | |
| SCHEMBL27680982 | 0.77 | — | — | |
| Ammonia Solution, Strong SCHEMBL5232391 | 0.75 | MAPT (0.31) | — | |
| SCHEMBL12500003 | 0.74 | POLB (0.31) | POLBTDP1 | |
| SCHEMBL7438175 | 0.71 | SLC1A2 (0.37) | SLC1A2MEN1BLMKMT2A | |
| Carbamic Acid SCHEMBL8907484 | 0.71 | — | — | |
| SCHEMBL312465 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4021910-A1 | NEW THERAPEUTIC AGENTS FOR THE TREATMENT OF HAEMATOLOGICAL PATHOLOGIES | Universita' degli Studi di Palermo (IT) | 2022-07-06 | — | — | EP | disclosed |
| WO-2021038452-A1 | NEW THERAPEUTIC AGENTS FOR THE TREATMENT OF HAEMATOLOGICAL PATHOLOGIES | UNIVERSITA' DEGLI STUDI DI PALERMO (IT) | 2021-03-04 | — | — | WO | disclosed |