Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL5232391

Cc1c2cccc1-2.N.O=C(O)C1CCNC2=CC=CCC21

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.31
PKM P14618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2308470 0.86 SLC1A2 (0.34)
SCHEMBL4078899 0.75
SCHEMBL27680982 0.72
SCHEMBL5309327 0.68 MAPT (0.37) MAPTPKM
SCHEMBL7368083 0.68 GRM4 (0.31)
SCHEMBL7014956 0.68 MAPT (0.41) MAPTPKM
SCHEMBL7444838 0.65
SCHEMBL3919444 0.63 ALDH1A1 (0.33)
Ammonia Solution, Strong SCHEMBL5316774 0.62 HSD11B1 (0.31)
Carbamic Acid SCHEMBL8907484 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1812080-A2 GPR41 AND MODULATORS THEREOF FOR THE TREATMENT OF INSULIN-RELATED DISORDERS Arena Pharmaceuticals, Inc. (US) 2007-08-01 EP claimed
WO-2006052566-A2 GPR41 AND MODULATORS THEREOF FOR THE TREATMENT OF INSULIN-RELATED DISORDERS ARENA PHARMACEUTICALS, INC. (US) 2006-05-18 WO claimed
EP-1812080-A2 GPR41 AND MODULATORS THEREOF FOR THE TREATMENT OF INSULIN-RELATED DISORDERS Arena Pharmaceuticals, Inc. (US) 2007-08-01 EP disclosed
WO-2006052566-A2 GPR41 AND MODULATORS THEREOF FOR THE TREATMENT OF INSULIN-RELATED DISORDERS ARENA PHARMACEUTICALS, INC. (US) 2006-05-18 WO disclosed