Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11767356 | 0.56 | TRPA1 (0.52) | CYP1A2CYP2D6KDM4ENPC1ALDH1A1 | |
| SCHEMBL9120194 | 0.53 | CYP1A2 (0.35) | CYP1A2CYP2D6KDM4ENPC1ALDH1A1 | |
| SCHEMBL28498734 | 0.53 | CYP1A2 (0.35) | CYP1A2CYP2D6KDM4ENPC1ALDH1A1 | |
| SCHEMBL29277268 | 0.53 | TSHR (0.41) | NPC1LMNAGAARAB9A | |
| SCHEMBL30589180 | 0.52 | CYP1A2 (0.50) | CYP1A2CYP2D6KDM4ENPC1ALDH1A1 | |
| SCHEMBL54645 | 0.52 | CYP1A2 (0.50) | CYP1A2CYP2D6KDM4ENPC1ALDH1A1 | |
| SCHEMBL25520 | 0.51 | TRPA1 (0.52) | CYP1A2CYP2D6KDM4ENPC1ALDH1A1 | |
| SCHEMBL20135905 | 0.51 | IDO1 (0.32) | KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL22983154 | 0.51 | NOS3 (0.52) | CYP1A2CYP2D6KDM4ENPC1ALDH1A1 | |
| SCHEMBL37435600 | 0.51 | CYP1A2 (0.36) | CYP1A2CYP2D6KDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021040999-A1 | METHODS AND COMPOSITIONS FOR STIMULATING EXOSOME SECRETION | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2021-03-04 | — | — | WO | disclosed |