Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 3/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | ITGAL | P20701 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2319073 | 0.82 | TRPA1 (0.39) | TRPA1CYP1A2CYP2D6MAOAMAOB | |
| SCHEMBL11767356 | 0.81 | TRPA1 (0.52) | TRPA1CYP1A2CYP2D6MAOAMAOB | |
| SCHEMBL9404574 | 0.80 | TRPA1 (0.38) | TRPA1CYP1A2CYP2D6MAOAMAOB | |
| SCHEMBL8834542 | 0.78 | TRPA1 (0.40) | TRPA1CYP1A2CYP2D6MAOAMAOB | |
| SCHEMBL19554 | 0.78 | TRPA1 (0.40) | TRPA1CYP1A2CYP2D6MAOAMAOB | |
| SCHEMBL1305958 | 0.78 | TRPA1 (0.40) | TRPA1CYP1A2CYP2D6MAOAMAOB | |
| SCHEMBL8668546 | 0.75 | MAOA (0.56) | TRPA1CYP1A2CYP2D6MAOAMAOB | |
| SCHEMBL3102452 | 0.75 | MAOA (0.56) | TRPA1CYP1A2CYP2D6MAOAMAOB | |
| SCHEMBL125113 | 0.75 | MAOA (0.56) | TRPA1CYP1A2CYP2D6MAOAMAOB | |
| SCHEMBL29724179 | 0.75 | MAOA (0.56) | TRPA1CYP1A2CYP2D6MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2571 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4361141-A1 | PROTEIN DEGRADATION AGENT | Suzhou Kintor Pharmaceuticals, Inc. (CN) | 2024-05-01 | — | — | EP | claimed |
| CN-117545749-A | Protein degradation agent | 苏州开拓药业股份有限公司 | 2024-02-09 | — | — | CN | claimed |
| WO-2024027694-A1 | PROTEIN DEGRADATION AGENT | 苏州开拓药业股份有限公司 | 2024-02-08 | — | — | WO | claimed |
| CN-117447452-A | Charge transport material, compound, delayed fluorescence material, and organic light-emitting element | 九州有机光材股份有限公司 | 2024-01-26 | — | — | CN | claimed |
| CN-114573507-B | Thermal activation delayed fluorescent material based on axial chiral ketone receptor and preparation method and application thereof | 中国科学院大学 | 2024-01-23 | — | — | CN | claimed |
| CN-116731060-A | Aromatic organic compound containing silicon and organic electroluminescent device containing same | 石家庄诚志永华显示材料有限公司 | 2023-09-12 | — | — | CN | claimed |
| CN-115947760-A | Pinene pyrimidine tetradentate platinum (II) and palladium (II) complex and preparation method and application thereof | 南京邮电大学 | 2023-04-11 | — | — | CN | claimed |
| CN-115850346-A | Pinene pyridazine tetradentate platinum (II) and palladium (II) complex based on intramolecular hydrogen bond, and preparation method and application thereof | 南京邮电大学 | 2023-03-28 | — | — | CN | claimed |
| CN-115716852-A | Sulfur-phosphorus heterocyclic receptor and nitrogen-containing heterocyclic donor compound, and synthesis method and application thereof | 黑龙江大学 | 2023-02-28 | — | — | CN | claimed |
| WO-2022268066-A1 | PROTEIN DEGRADATION AGENT | 苏州开拓药业股份有限公司 | 2022-12-29 | — | — | WO | claimed |
| US-5543422-A | HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS, FUNGICIDES | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1996-08-06 | — | — | US | claimed |
| WO-1995026347-A1 | THIAZOLIDINES AND OXAZOLIDINES SUBSTITUTED BY A PYRIDINE RING AND THEIR USE AS HYPOGLYCEMIC AGENTS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-05 | — | — | WO | claimed |
| EP-0662964-A1 | HETEROCYCLIC AMINES HAVING COLMODULIN ANTAGONIST PROPERTIES. | BRITISH TECH GROUP (GB) | 1995-07-19 | — | — | EP | claimed |
| EP-0654495-A1 | Photoconductive film formed from a grafted silane polymer; process for preparing and process for the formation of an electrostatic image of this film and an optical valve based on this film | FRANCE TELECOM (FR) | 1995-05-24 | — | — | EP | claimed |
| EP-0471236-B1 | Imidazopyridine derivatives and their use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-03-15 | — | — | EP | claimed |
| EP-0453197-B1 | Amine derivatives | ICI PLC (GB) | 1994-06-15 | — | — | EP | claimed |
| WO-1994007875-A1 | HETEROCYCLIC AMINES HAVING COLMODULIN ANTAGONIST PROPERTIES | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1994-04-14 | — | — | WO | claimed |
| EP-0471236-A1 | Imidazopyridine derivatives and their use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-02-19 | — | — | EP | claimed |
| EP-0453197-A1 | Amine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-23 | — | — | EP | claimed |
| US-3946011-A | S-Triazine tetracarboxylic acids and dianhydrides | CIBA-GEIGY CORPORATION (US) | 1976-03-23 | — | — | US | claimed |