Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4Z1 | Q86W10 | 5/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.34 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.33 |
| ▸ | NAAA | Q02083 | 2/20 | 0.33 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32679965 | 0.95 | CYP4Z1 (0.36) | CYP4Z1NAMPTNR1H2NR1H3SETD7 | |
| SCHEMBL1723366 | 0.83 | P2RX4 (0.35) | SETD7P2RX4P2RX1P2RX3MTNR1A | |
| SCHEMBL6248335 | 0.75 | PSEN1 (0.38) | NR1H2NR1H3P2RX4P2RX1P2RX3 | |
| SCHEMBL27733597 | 0.74 | NAMPT (0.53) | NAMPTASAH1P2RX4NAAA | |
| SCHEMBL8472507 | 0.74 | P2RX4 (0.37) | P2RX4P2RX1P2RX3MTNR1AMTNR1B | |
| SCHEMBL27812916 | 0.73 | KDM4E (0.42) | NR1H2NR1H3SETD7KDM4ELMNA | |
| SCHEMBL27843685 | 0.73 | KDM4E (0.42) | NR1H2NR1H3SETD7KDM4ELMNA | |
| SCHEMBL31202626 | 0.73 | KDM4E (0.42) | NR1H2NR1H3SETD7KDM4ELMNA | |
| SCHEMBL27833019 | 0.73 | KDM4E (0.42) | NR1H2NR1H3SETD7KDM4ELMNA | |
| SCHEMBL9158078 | 0.73 | KDM4E (0.42) | NR1H2NR1H3SETD7KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4021441-A1 | MEMBRANE-ACTIVE ANTI-BACTERIAL COMPOUNDS AND USES THEREOF | Trustees of Dartmouth College (US) | 2022-07-06 | — | — | EP | disclosed |
| WO-2021042046-A1 | MEMBRANE-ACTIVE ANTI-BACTERIAL COMPOUNDS AND USES THEREOF | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2021-03-04 | — | — | WO | disclosed |