Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 3/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.33 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.33 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32679965 | 0.76 | CYP4Z1 (0.36) | P2RX4P2RX1P2RX3GAANR1H2 | |
| SCHEMBL23043877 | 0.75 | CYP4Z1 (0.37) | P2RX4P2RX1P2RX3KDM4ENR1H2 | |
| SCHEMBL1723366 | 0.72 | P2RX4 (0.35) | P2RX4P2RX1P2RX3ALDH1A1MAPT | |
| SCHEMBL3966811 | 0.70 | MEN1 (0.33) | P2RX4P2RX1P2RX3ALDH1A1MAPT | |
| SCHEMBL8472507 | 0.70 | P2RX4 (0.37) | P2RX4P2RX1P2RX3PTBP1SMN1; SMN2 | |
| SCHEMBL4240875 | 0.69 | CA2 (0.36) | NR1H2NR1H3SMN1; SMN2 | |
| Sulfuric Acid SCHEMBL27824625 | 0.68 | CDC25A (0.41) | P2RX4P2RX1P2RX3ALDH1A1KDM4E | |
| Sulfuric Acid SCHEMBL27824624 | 0.68 | CDC25A (0.41) | P2RX4P2RX1P2RX3ALDH1A1KDM4E | |
| SCHEMBL6248333 | 0.68 | PSEN1 (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL3975056 | 0.68 | CES1 (0.36) | ALDH1A1MAPTKDM4EGAANR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590348-A1 | ARYL / HETARYL SUBSTITUTED IMIDAZOQUINOLINES | 3M Innovative Properties Company (US) | 2005-11-02 | — | — | EP | disclosed |
| WO-2004058759-A1 | ARYL / HETARYL SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2004-07-15 | — | — | WO | disclosed |