SCHEMBL23045161

SCHEMBL23045161

C[Si](C)(C)C([SiH3])=Cc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.43
TSHR P16473 1/20 0.43
AKR1C3 P42330 1/20 0.43
FBP1 P09467 3/20 0.39
AKR1C1 Q04828 1/20 0.38
ESR1 P03372 1/20 0.38
KDM1A O60341 1/20 0.37
RECQL P46063 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
LMNA P02545 1/20 0.37
NISCH Q9Y2I1 1/20 0.37
CYP19A1 P11511 1/20 0.36
CYP11B2 P19099 1/20 0.36
HTT P42858 1/20 0.36
NR1I2 O75469 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL140742 0.78 ALDH1A1 (0.54) ALDH1A1TSHRAKR1C3FBP1AKR1C1
SCHEMBL8072809 0.75 ALDH1A1 (0.48) ALDH1A1TSHRAKR1C3FBP1AKR1C1
SCHEMBL19206366 0.74 ALDH1A1 (0.50) ALDH1A1TSHRAKR1C3FBP1AKR1C1
SCHEMBL5748410 0.73 ALDH1A1 (0.43) ALDH1A1TSHRAKR1C3FBP1AKR1C1
SCHEMBL9412801 0.72 ALDH1A1 (0.39) ALDH1A1TSHRAKR1C3FBP1AKR1C1
SCHEMBL28912798 0.71 AKR1C1 (0.45) ALDH1A1TSHRAKR1C3FBP1AKR1C1
SCHEMBL31565146 0.69 ALDH1A1 (0.40) ALDH1A1TSHRAKR1C3FBP1AKR1C1
SCHEMBL9153625 0.69 ALDH1A1 (0.54) ALDH1A1TSHRAKR1C3FBP1AKR1C1
SCHEMBL19245191 0.69 ALDH1A1 (0.54) ALDH1A1TSHRAKR1C3FBP1AKR1C1
SCHEMBL18918379 0.69 MCL1 (0.45) ALDH1A1TSHRAKR1C3FBP1AKR1C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112218901-B Vinyl ether group-containing (meth) acrylate polymer, process for producing the same, and polymer composition 株式会社日本触媒 2023-08-25 CN disclosed
CN-114341215-A Curable composition 株式会社日本触媒 2022-04-12 CN disclosed
WO-2021039799-A1 CURABLE COMPOSITION 株式会社日本触媒 2021-03-04 WO disclosed
WO-2021039801-A1 CURABLE COMPOSITION 株式会社日本触媒 2021-03-04 WO disclosed
CN-112218901-A Method for producing vinyl ether group-containing (meth) acrylate polymer, and polymer composition 株式会社日本触媒 2021-01-12 CN disclosed