SCHEMBL23045720

SCHEMBL23045720

CC(C)CCC(=O)NC(Cc1ccc(N)nc1)C(=O)c1nc2ccccc2s1

nearest known ligand 0.51

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CMA1 P23946 2/20 0.51
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
CASP1 P29466 1/20 0.43
ALDH1A1 P00352 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23042473 0.83 CMA1 (0.43) CMA1ALOX15TSHRCASP1
SCHEMBL23042474 0.83 CMA1 (0.43) CMA1ALOX15TSHRCASP1
SCHEMBL6803362 0.81 ALOX15 (0.49) CMA1ALOX15TSHRCASP1ALDH1A1
SCHEMBL22850490 0.77 ALDH1A1 (0.46) ALOX15TSHRCASP1ALDH1A1KMT2A
SCHEMBL23042502 0.73 CMA1 (0.45) CMA1ALOX15TSHRCASP1
SCHEMBL23042501 0.73 CMA1 (0.45) CMA1ALOX15TSHRCASP1
SCHEMBL1667573 0.70 SMN1; SMN2 (0.56) CMA1ALOX15TSHRCASP1ALDH1A1
SCHEMBL1667049 0.70 SMN1; SMN2 (0.56) CMA1ALOX15TSHRCASP1ALDH1A1
SCHEMBL21028551 0.69
SCHEMBL19334529 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021040349-A1 NOVEL HEPSIN INHIBITOR AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE COMPONENT FOR PREVENTING OR TREATING METASTATIC CANCER 고려대학교 세종산학협력단 2021-03-04 WO disclosed