Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6803359 | 0.83 | ALOX15 (0.47) | ALOX15TSHRCASP1L3MBTL1NPC1 | |
| SCHEMBL7032673 | 0.82 | ALOX15 (0.46) | ALOX15TSHRCASP1L3MBTL1NPC1 | |
| SCHEMBL6463758 | 0.82 | CNR1 (0.51) | NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL23045720 | 0.81 | CMA1 (0.51) | ALOX15TSHRCASP1ALDH1A1KMT2A | |
| SCHEMBL22850490 | 0.80 | ALDH1A1 (0.46) | ALOX15TSHRCASP1ALDH1A1KMT2A | |
| SCHEMBL7240741 | 0.80 | ALOX15 (0.44) | ALOX15TSHRCASP1L3MBTL1NPC1 | |
| SCHEMBL1667049 | 0.79 | SMN1; SMN2 (0.56) | ALOX15TSHRCASP1L3MBTL1NPC1 | |
| SCHEMBL1667573 | 0.79 | SMN1; SMN2 (0.56) | ALOX15TSHRCASP1L3MBTL1NPC1 | |
| SCHEMBL7032670 | 0.78 | ALOX15 (0.44) | ALOX15TSHRCASP1L3MBTL1NPC1 | |
| SCHEMBL6463431 | 0.78 | CTSL (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6730671-B2 | ENZYME INHIBITOR TREATING AUTOIMMUNE DISEASES, ALZHEIMER'S DISEASE, ATHEROSCLEROSIS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2004-05-04 | — | — | US | disclosed |