Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 13/20 | 1.00 |
| ▸ | CES1 | P23141 | 7/20 | 1.00 |
| ▸ | CES2 | O00748 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | MGLL | Q99685 | 1/20 | 0.61 |
| ▸ | PLA2G4C | Q9UP65 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2819894 | 1.00 | FAAH (1.00) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL28471077 | 1.00 | FAAH (1.00) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL810234 | 1.00 | FAAH (1.00) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL31152148 | 1.00 | FAAH (1.00) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL10966855 | 1.00 | FAAH (1.00) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL9192692 | 1.00 | FAAH (1.00) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL4653611 | 1.00 | FAAH (1.00) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL8515257 | 1.00 | FAAH (1.00) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL463411 | 0.98 | FAAH (1.00) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL809819 | 0.90 | FAAH (0.86) | FAAHCES1CES2MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970195-B1 | FATTY-ACID AMIDE HYDROLASE | SCRIPPS RESEARCH INST (US) | 2007-10-17 | — | — | EP | claimed |
| EP-0833899-B1 | CIS-9,10-OCTADECENOAMIDASE | SCRIPPS RESEARCH INST (US) | 2005-01-19 | — | — | EP | claimed |
| WO-2011102540-A1 | MATERIAL FOR REMOVING CAUXIN IN CAT URINE | 国立大学法人千葉大学 (JP) | 2011-08-25 | — | — | WO | disclosed |