SCHEMBL809819

SCHEMBL809819

CCCCC(=O)C(F)(F)F

nearest known ligand 0.86

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FAAH O00519 13/20 0.86
CES1 P23141 8/20 0.82
CES2 O00748 3/20 0.82
MEN1 O00255 1/20 0.82
CYP1A2 P05177 1/20 0.82
KMT2A Q03164 1/20 0.82
HSD17B10 Q99714 1/20 0.82
ALDH1A1 P00352 1/20 0.60
PLA2G4B P0C869 1/20 0.60
MAPT P10636 1/20 0.60
PLA2G4A P47712 1/20 0.60
BLM P54132 1/20 0.60
MGLL Q99685 1/20 0.60
PLA2G4C Q9UP65 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL463411 0.92 FAAH (1.00) FAAHCES1CES2MEN1CYP1A2
SCHEMBL9192692 0.90 FAAH (1.00) FAAHCES1CES2MEN1CYP1A2
SCHEMBL8515257 0.90 FAAH (1.00) FAAHCES1CES2MEN1CYP1A2
SCHEMBL810234 0.90 FAAH (1.00) FAAHCES1CES2MEN1CYP1A2
SCHEMBL28471077 0.90 FAAH (1.00) FAAHCES1CES2MEN1CYP1A2
SCHEMBL10966855 0.90 FAAH (1.00) FAAHCES1CES2MEN1CYP1A2
SCHEMBL4653611 0.90 FAAH (1.00) FAAHCES1CES2MEN1CYP1A2
SCHEMBL2819894 0.90 FAAH (1.00) FAAHCES1CES2MEN1CYP1A2
SCHEMBL31152148 0.90 FAAH (1.00) FAAHCES1CES2MEN1CYP1A2
SCHEMBL2304645 0.90 FAAH (1.00) FAAHCES1CES2MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007121851-A1 LIGHTENING AND/OR COLOURING AGENTS COMPRISING HALOGENATED KETONES HENKEL AG & CO. KGAA (DE) 2007-11-01 WO claimed
EP-1420771-A2 USE OF TRIFLUOROACETYL ALKYL-SUBSTITUTED PHENYL DERIVATIVES, PHENOL DERIVATIVES, AND BENZOYL DERIVATIVES IN THE TREATMENT AND/OR PROPHYLAXIS OF OBESITY AND ACCOMPANYING DISEASES AND/OR SECONDARY DISEASES Solvay Pharmaceuticals GmbH (DE) 2004-05-26 EP claimed
WO-2003007923-A2 USE OF TRIFLUOROACETYL ALKYL-SUBSTITUTED PHENYL DERIVATIVES, PHENOL DERIVATIVES, AND BENZOYL DERIVATIVES IN THE TREATMENT AND/OR PROPHYLAXIS OF OBESITY AND ACCOMPANYING DISEASES AND/OR SECONDARY DISEASES SOLVAY PHARMACEUTICALS GMBH (DE) 2003-01-30 WO claimed
CN-118562175-B Block all-carbon-connected proton exchange membrane and preparation method and application thereof 佛山大学 2025-04-01 CN disclosed
WO-2025057814-A1 PHOTOCHROMIC COMPOSITION, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES 株式会社トクヤマ 2025-03-20 WO disclosed
CN-118562175-A Block all-carbon-connected proton exchange membrane and preparation method and application thereof 佛山科学技术学院 2024-08-30 CN disclosed
EP-4245369-A2 NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF Sage Therapeutics, Inc. (US) 2023-09-20 EP disclosed
EP-4246641-A1 ELECTROLYTE, AS WELL AS ELECTROCHEMICAL APPARATUS AND ELECTRONIC APPARATUS CONTAINING THE SAME Ningde Amperex Technology Ltd. (CN) 2023-09-20 EP disclosed
US-20230218638-A1 NEUROACTIVE COMPOUNDS AND METHODS OF USE THEREOF SAGE THERAPEUTICS, INC. 2023-07-13 US disclosed
EP-3865135-A2 NEUROACTIVE STEROIDS FOR USE IN THERAPY Sage Therapeutics, Inc. (US) 2021-08-18 EP disclosed
EP-3677259-A1 USE OF ARACHIDONYL TRIFLUOROMETHYL KETONE Mosaiques Diagnostics And Therapeutics AG (DE) 2020-07-08 EP disclosed
WO-2007104582-A1 TETRAHYDRONAPHTHALINE DERIVATIVES, METHODS FOR THE PRODUCTION AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2007-09-20 WO disclosed
US-20060229333-A1 Quinoline and isoquinoline derivatives, a process for their production and their use as inflammation inhibitors BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2006-10-12 US disclosed
EP-0300497-B1 Optically active compound, process for producing same and liquid crystal composition containing same CANON KK (JP) 1994-03-02 EP disclosed
US-5126071-A Optically active compound, process for producing same and liquid crystal composition containing same CANON KABUSHIKI KAISHA (JP) 1992-06-30 US disclosed
US-4917817-A Optical active compound, process for producing same and liquid crystal composition containing same CANON KABUSHIKI KAISHA (JP) 1990-04-17 US disclosed
EP-0300497-A1 Optically active compound, process for producing same and liquid crystal composition containing same CANON KABUSHIKI KAISHA (JP) 1989-01-25 EP disclosed
EP-0002892-B1 AMIDE DERIVATIVES, PROCESS FOR THEIR MANUFACTURE AND PHARMACEUTICAL OR VETERINARY COMPOSITIONS CONTAINING THEM IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-02-06 EP disclosed
US-4191775-A ANTIANDROGENIC IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-03-04 US disclosed
EP-0002892-A1 Amide derivatives, process for their manufacture and pharmaceutical or veterinary compositions containing them IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1979-07-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060229333-A1 Quinoline and isoquinoline derivatives, a process for their production and their use as inflammation inhibitors NFKBIA, IL1B, IRF3 FAAH 1197/4885CES1 1071/4885CES2 2510/4885
US-20230218638-A1 NEUROACTIVE COMPOUNDS AND METHODS OF USE THEREOF GRIN3B, GRIN2A, GRIN1 FAAH 854/4885CES1 915/4885CES2 348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.