SCHEMBL463411

SCHEMBL463411

CCCCCC(=O)C(F)(F)F

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FAAH O00519 13/20 1.00
CES1 P23141 7/20 0.95
CES2 O00748 4/20 0.95
MEN1 O00255 1/20 0.95
CYP1A2 P05177 1/20 0.95
KMT2A Q03164 1/20 0.95
HSD17B10 Q99714 1/20 0.95
ALDH1A1 P00352 1/20 0.63
PLA2G4B P0C869 1/20 0.63
MAPT P10636 1/20 0.63
PLA2G4A P47712 1/20 0.63
BLM P54132 1/20 0.63
MGLL Q99685 1/20 0.63
PLA2G4C Q9UP65 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL810234 0.98 FAAH (1.00) FAAHCES1CES2MEN1CYP1A2
SCHEMBL2304645 0.98 FAAH (1.00) FAAHCES1CES2MEN1CYP1A2
SCHEMBL8515257 0.98 FAAH (1.00) FAAHCES1CES2MEN1CYP1A2
SCHEMBL28471077 0.98 FAAH (1.00) FAAHCES1CES2MEN1CYP1A2
SCHEMBL31152148 0.98 FAAH (1.00) FAAHCES1CES2MEN1CYP1A2
SCHEMBL9192692 0.98 FAAH (1.00) FAAHCES1CES2MEN1CYP1A2
SCHEMBL4653611 0.98 FAAH (1.00) FAAHCES1CES2MEN1CYP1A2
SCHEMBL2819894 0.98 FAAH (1.00) FAAHCES1CES2MEN1CYP1A2
SCHEMBL10966855 0.98 FAAH (1.00) FAAHCES1CES2MEN1CYP1A2
SCHEMBL809819 0.92 FAAH (0.86) FAAHCES1CES2MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024106828-A1 FLUORENE-BASED BRANCHED COPOLYMER POLYMER ELECTROLYTE MEMBRANE 경상국립대학교산학협력단 2024-05-23 WO claimed
WO-2024029917-A1 BRANCHED COPOLYMER PROTON EXCHANGE MEMBRANE COMPRISING NAFION-GRAFTED GRAPHENE OXIDE AND WATER ELECTROLYSIS SYSTEM USING SAME 경상국립대학교산학협력단 2024-02-08 WO claimed
WO-2023085592-A1 FLUORENE- AND BIPHENYL-BASED BRANCHED COPOLYMER POLYMER ELECTROLYTE MEMBRANE AND WATER ELECTROLYSIS SYSTEM USING SAME 경상국립대학교 산학협력단 2023-05-19 WO claimed
US-11236196-B2 Polymers and methods for their manufacture RENSSELAER POLYTECHNIC INSTITUTE (US) 2022-02-01 US claimed
US-20200172659-A1 NOVEL POLYMERS AND METHODS FOR THEIR MANUFACTURE RENSSELAER POLYTECHNIC INSTITUTE (US) 2020-06-04 US claimed
WO-2016003673-A1 FLUORONATION OF α -HALOALKYL KETONES COORSTEK FLUOROCHEMICALS, INC. (US) 2016-01-07 WO claimed
US-4758380-A Substituted 1,1,1-triaryl-2,2,2-trifluoroethanes and processes for their synthesis THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1988-07-19 US claimed
US-20250243310-A1 ANION EXCHANGE BRANCHED CO-POLYMER WITH POLY(ARYL) AND A BRANCHED COMPOUND AND QUINUCLIDINIUM SIDE CHAINS AND SYNTHESIS THEREOF USA FORTESCUE IP INC (US) 2025-07-31 US disclosed
US-12283729-B2 Anion exchange branched co-polymer with poly(aryl) and a branched compound and quinuclidinium side chains and synthesis thereof USA FORTESCUE IP INC (US) 2025-04-22 US disclosed
CN-118562175-B Block all-carbon-connected proton exchange membrane and preparation method and application thereof 佛山大学 2025-04-01 CN disclosed
US-20250062377-A1 ANION EXCHANGE BRANCHED CO-POLYMER WITH POLY(ARYL) AND A BRANCHED COMPOUND AND QUINUCLIDINIUM SIDE CHAINS AND SYNTHESIS THEREOF USA FORTESCUE IP INC (US) 2025-02-20 US disclosed
CN-119286021-A Fluorine-containing micro-block polyarylalkyl anion exchange membrane and preparation method thereof 安徽大学 2025-01-10 CN disclosed
WO-2024216181-A1 ANION EXCHANGE BRANCHED CO-POLYMER WITH POLY(ARYL) AND A BRANCHED COMPOUND AND QUINUCLIDINIUM SIDE CHAINS AND SYNTHESIS THEREOF USA Fortescue IP, Inc. (US) 2024-10-17 WO disclosed
US-4912238-A Cyclization of a teracarboxy-substituted 1,1,1-triaryl-2,2,2-trifluoroethane compound in presence of acetic anhydride THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1990-03-27 US disclosed
US-4885116-A Substituted 1,1,1-triaryl-2,2,2-trifluoroethanes and processes for their synthesis THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1989-12-05 US disclosed
US-4845167-A Condensation polyimides containing 1,1,1-triaryl-2,2,2-trifluoroethane structures THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1989-07-04 US disclosed
US-4758380-A Substituted 1,1,1-triaryl-2,2,2-trifluoroethanes and processes for their synthesis THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1988-07-19 US disclosed
US-4315020-A Oxazoline (trifluoroethyl) amine SCIENCE UNION ET CIE (FR) 1982-02-09 US disclosed
US-4315019-A Novel aryltrifluoroethylamines and processes for producing the same SCIENCE UNION ET CIE (FR) 1982-02-09 US disclosed
US-4267345-A 2-//PYRROL-2-YL, THIEN-2-YL, OR FUR-2-YL/-ALPHA-TRIFLUOROALKYL-AMINOOXAZOLINES; HYPOTENSIVE AGENTS SCIENCE UNION ET CIE (FR) 1981-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11236196-B2 Polymers and methods for their manufacture EPCAM, PKM, PHOSPHO1 FAAH 1788/4885CES1 1687/4885CES2 207/4885
US-20200172659-A1 NOVEL POLYMERS AND METHODS FOR THEIR MANUFACTURE EPCAM, PKM, PXMP4 FAAH 2074/4885CES1 1934/4885CES2 333/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.