Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20581860 | 0.88 | FOLH1 (0.54) | LMNAMAPTL3MBTL1NPC1CYP2C9 | |
| SCHEMBL9706496 | 0.88 | PARP1 (0.52) | PARP1HTTLMNASIRT2MAPT | |
| SCHEMBL30184648 | 0.87 | PARP1 (0.54) | PARP1HTTSIRT2MAPTL3MBTL1 | |
| SCHEMBL7689226 | 0.81 | PARP1 (0.61) | PARP1HTTLMNASIRT2MAPT | |
| SCHEMBL29179263 | 0.79 | MRGPRX4 (0.52) | MAPTL3MBTL1NPC1CYP2C9CYP2C19 | |
| SCHEMBL2229263 | 0.77 | FOLH1 (0.57) | MAPTL3MBTL1CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL28840214 | 0.77 | PARP10 (0.47) | PARP1HTTLMNASIRT2NPC1 | |
| SCHEMBL718082 | 0.77 | PARP1 (0.79) | PARP1HTTLMNAMAPTNPC1 | |
| SCHEMBL4143247 | 0.77 | NPC1 (0.52) | PARP1HTTLMNASIRT2MAPT | |
| Hydrochloric Acid SCHEMBL514324 | 0.76 | FOLH1 (0.56) | MAPTL3MBTL1CYP2C9CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10933051-B2 | Carbapenem compounds and compositions for the treatment of bacterial infections | FOB SYNTHESIS, INC. (US) | 2021-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10933051-B2 | Carbapenem compounds and compositions for the treatment of bacterial infections | SLC11A2, GSK3B, GSK3A | PARP1 158/4885HTT 4815/4885LMNA 739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.