Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 2/20 | 0.45 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23046594 | 0.88 | PARP1 (0.50) | PARP1HTTLMNASIRT2MAPT | |
| SCHEMBL9650260 | 0.88 | FOLH1 (0.56) | LMNAMAPTL3MBTL1MRGPRX4NPC1 | |
| SCHEMBL9183339 | 0.85 | F10 (0.45) | HTTMAPTL3MBTL1MRGPRX4NPC1 | |
| SCHEMBL9706350 | 0.85 | L3MBTL1 (0.49) | LMNAMAPTL3MBTL1MRGPRX4NPC1 | |
| SCHEMBL9341896 | 0.85 | MAPT (0.63) | LMNAMAPTL3MBTL1MRGPRX4NPC1 | |
| Hydrochloric Acid SCHEMBL9183067 | 0.84 | F2 (0.44) | HTTMAPTL3MBTL1MRGPRX4NPC1 | |
| SCHEMBL19285699 | 0.81 | KDM1A (0.50) | PARP1HTTLMNAMAPTL3MBTL1 | |
| SCHEMBL30765090 | 0.80 | HTT (0.48) | HTTMRGPRX4PARP10PARP15 | |
| SCHEMBL30184648 | 0.80 | PARP1 (0.54) | PARP1HTTSIRT2MAPTL3MBTL1 | |
| SCHEMBL718082 | 0.79 | PARP1 (0.79) | PARP1HTTLMNAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500210-A2 | Liquid crystal compounds and compositions | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 1992-08-26 | — | — | EP | disclosed |