Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.51 |
| ▸ | MYC | P01106 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.49 |
| ▸ | CTSV | O60911 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL514324 | 0.98 | FOLH1 (0.56) | FOLH1L3MBTL1MAPTCYP2C9CYP2C19 | |
| SCHEMBL3424839 | 0.91 | ALDH1A1 (0.55) | FOLH1L3MBTL1MAPTCYP2C9CYP2C19 | |
| SCHEMBL14882633 | 0.91 | CTSV (0.53) | FOLH1L3MBTL1MAPTCYP2C9CYP2C19 | |
| SCHEMBL26021326 | 0.87 | MAPT (0.65) | FOLH1L3MBTL1MAPTCYP2C9CYP2C19 | |
| SCHEMBL30184648 | 0.87 | PARP1 (0.54) | FOLH1L3MBTL1MAPTCYP2C9CYP2C19 | |
| SCHEMBL9724220 | 0.87 | FOLH1 (0.55) | FOLH1L3MBTL1MAPTCYP2C9CYP2C19 | |
| SCHEMBL514323 | 0.87 | L3MBTL1 (0.50) | FOLH1L3MBTL1MAPTCYP2C9CYP2C19 | |
| SCHEMBL1305739 | 0.87 | PTGER1 (0.61) | FOLH1L3MBTL1MAPTTDP1ALDH1A1 | |
| SCHEMBL24983833 | 0.86 | PTGER1 (0.60) | FOLH1L3MBTL1MAPTCYP2C9CYP2C19 | |
| SCHEMBL11110377 | 0.86 | MCL1 (0.55) | FOLH1L3MBTL1MAPTCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240336588-A1 | COMPOSITIONS AND METHODS FOR ANTIOXIDANT AND ANTI-INFLAMMATORY THERAPEUTICS | AVANTI BIOSCIENCES, INC. | 2024-10-10 | — | — | US | disclosed |
| CN-118076589-A | Amide compound, preparation method and pharmaceutical application thereof | 中国科学院上海药物研究所 | 2024-05-24 | — | — | CN | disclosed |
| EP-4370113-A1 | COMPOSITIONS AND METHODS FOR ANTIOXIDANT AND ANTI-INFLAMMATORY THERAPEUTICS | Avanti Biosciences Inc. (US) | 2024-05-22 | — | — | EP | disclosed |
| CN-117794526-A | Compositions and methods for antioxidants and anti-inflammatory therapeutics | 阿万蒂生物科学股份有限公司 | 2024-03-29 | — | — | CN | disclosed |
| WO-2023168240-A1 | SMALL MOLECULE INHIBITORS OF ENPP1 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-09-07 | — | — | WO | disclosed |
| WO-2023288020-A1 | COMPOSITIONS AND METHODS FOR ANTIOXIDANT AND ANTI-INFLAMMATORY THERAPEUTICS | AVANTI BIOSCIENCES INC. (US) | 2023-01-19 | — | — | WO | disclosed |
| WO-2023288020-A1 | COMPOSITIONS AND METHODS FOR ANTIOXIDANT AND ANTI-INFLAMMATORY THERAPEUTICS | AVANTI BIOSCIENCES INC. (US) | 2023-01-19 | — | — | WO | disclosed |
| WO-2022268145-A1 | AMIDE COMPOUND, AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | 中国科学院上海药物研究所 | 2022-12-29 | — | — | WO | disclosed |
| CN-115504940-A | Amide compound, preparation method and pharmaceutical application thereof | 中国科学院上海药物研究所 | 2022-12-23 | — | — | CN | disclosed |
| EP-2917203-B1 | METHOD FOR IDENTIFYING MYC INHIBITORS | DANA FARBER CANCER INST INC (US) | 2019-04-03 | — | — | EP | disclosed |
| US-9567301-B2 | Pyrrol-1-yl benzoic acid derivatives useful as myc inhibitors | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-02-14 | — | — | US | disclosed |
| US-9370529-B2 | Tannin inhibitors of HIV | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2016-06-21 | — | — | US | disclosed |
| US-20160038520-A1 | TANNIN INHIBITORS OF HIV | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2016-02-11 | — | — | US | disclosed |
| US-8901317-B2 | Tryptamine derivatives, their preparation and their use in gastropathy | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-12-02 | — | — | US | disclosed |
| US-20130197052-A1 | TRYPTAMINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN GASTROPATHY | UNIVERSITY OF CALCUTTA (IN) | 2013-08-01 | — | — | US | disclosed |
| WO-2011085454-A1 | GP120 -BINDING BENZENE COMPOUNDS AND SACCHARIDE COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN K.U.LEUVEN R&D (BE) | 2011-07-21 | — | — | WO | disclosed |
| EP-1171130-A4 | PHARMACEUTICAL COMPOSITIONS CONTAINING POLY(ADP-RIBOSE) GLYCOHYDROLASE INHIBITORS AND METHODS OF USING THE SAME | GUILFORD PHARM INC (US) | 2004-05-19 | — | — | EP | disclosed |
| EP-1171130-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING POLY(ADP-RIBOSE) GLYCOHYDROLASE INHIBITORS AND METHODS OF USING THE SAME | GUILFORD PHARMACEUTICALS INC. (US) | 2002-01-16 | — | — | EP | disclosed |
| WO-2000025787-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING POLY(ADP-RIBOSE) GLYCOHYDROLASE INHIBITORS AND METHODS OF USING THE SAME | GUILFORD PHARMACEUTICALS INC. (US) | 2000-05-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240336588-A1 | COMPOSITIONS AND METHODS FOR ANTIOXIDANT AND ANTI-INFLAMMATORY THERAPEUTICS | MPO, GPX4, GPX1 | FOLH1 1463/4885L3MBTL1 4489/4885MAPT 1586/4885 |
| US-20130197052-A1 | TRYPTAMINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN GASTROPATHY | HTRA2, AIFM1, SI | FOLH1 2144/4885L3MBTL1 3343/4885MAPT 4040/4885 |
| US-20160038520-A1 | TANNIN INHIBITORS OF HIV | SERPINB1, TSN, FURIN | FOLH1 2739/4885L3MBTL1 3830/4885MAPT 328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.