Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.70 |
| ▸ | MEN1 | O00255 | 11/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18919152 | 0.86 | MEN1 (0.76) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL18919149 | 0.86 | MEN1 (0.76) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL16789343 | 0.84 | MEN1 (0.50) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL18932674 | 0.79 | KMT2A (0.66) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| Acetic Acid SCHEMBL28679441 | 0.75 | MAPT (0.60) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL13723527 | 0.75 | MAPT (1.00) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL13723525 | 0.75 | MAPT (1.00) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL12807535 | 0.74 | MAPT (0.59) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL31264349 | 0.73 | KMT2A (0.57) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL7832814 | 0.73 | MAPT (0.67) | MAPTKMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11117907-B2 | Curcuminoid-inspired synthetic compounds as anti-tumor agents | UNIVERSITY OF NORTH FLORIDA BOARD OF TRUSTEES (US) | 2021-09-14 | — | — | US | disclosed |
| US-20210087208-A1 | NOVEL CURCUMINOID-INSPIRED SYNTHETIC COMPOUNDS AS ANTI-TUMOR AGENTS | UNIVERSITY OF NORTH FLORIDA BOARD OF TRUSTEES (US) | 2021-03-25 | — | — | US | disclosed |
| US-10934241-B2 | Curcuminoid-inspired synthetic compounds as anti-tumor agents | UNIVERSITY OF NORTH FLORIDA BOARD OF TRUSTEES (US) | 2021-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11117907-B2 | Curcuminoid-inspired synthetic compounds as anti-tumor agents | FOXO3, IKZF3, FOXO1 | MAPT 3888/4885KMT2A 2374/4885MEN1 3985/4885 |
| US-20210087208-A1 | NOVEL CURCUMINOID-INSPIRED SYNTHETIC COMPOUNDS AS ANTI-TUMOR AGENTS | IKZF3, FOXO3, FOXO1 | MAPT 4211/4885KMT2A 2093/4885MEN1 4287/4885 |
| US-10934241-B2 | Curcuminoid-inspired synthetic compounds as anti-tumor agents | FOXO3, FOXO1, IKZF3 | MAPT 4166/4885KMT2A 1477/4885MEN1 3417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.