Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23047469 | 0.86 | RAB9A (0.43) | KMT2AMEN1L3MBTL1ALDH1A1RAB9A | |
| SCHEMBL14706051 | 0.84 | ALDH1A1 (0.44) | KMT2AMEN1L3MBTL1ALDH1A1RAB9A | |
| SCHEMBL14705931 | 0.83 | ALDH1A1 (0.62) | KMT2AMEN1ALDH1A1RAB9ANPC1 | |
| SCHEMBL14705744 | 0.83 | ALDH1A1 (0.59) | KMT2AMEN1L3MBTL1ALDH1A1RAB9A | |
| SCHEMBL14705933 | 0.83 | KMT2A (0.59) | KMT2AMEN1ALDH1A1RAB9ARECQL | |
| SCHEMBL14706047 | 0.83 | SMN1; SMN2 (0.50) | KMT2AMEN1ALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL23035227 | 0.83 | ALDH1A1 (0.43) | KMT2AMEN1L3MBTL1ALDH1A1RAB9A | |
| SCHEMBL23047463 | 0.83 | ALDH1A1 (0.62) | KMT2AMEN1ALDH1A1RAB9ANPC1 | |
| SCHEMBL14705943 | 0.83 | DDX3X (0.44) | KMT2AMEN1L3MBTL1ALDH1A1RAB9A | |
| SCHEMBL14705942 | 0.83 | KMT2A (0.59) | KMT2AMEN1ALDH1A1RAB9ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2742019-B1 | N1-CYCLIC AMINE-N5-SUBSTITUTED PHENYL BIGUANIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | IMMUNOMET THERAPEUTICS INC (US) | 2021-03-03 | — | — | EP | disclosed |