Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.33 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.33 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.33 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | BRD1 | O95696 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18680837 | 0.77 | HDAC1 (0.37) | HDAC1HDAC6ACHEMAPTKMT2A | |
| SCHEMBL4137051 | 0.76 | ACHE (0.40) | HDAC1HDAC6ACHEMAPTKMT2A | |
| SCHEMBL4126437 | 0.76 | ACHE (0.40) | HDAC1HDAC6ACHEMAPTKMT2A | |
| SCHEMBL24477868 | 0.76 | HDAC1 (0.39) | HDAC1HDAC6ACHEMAPTKMT2A | |
| SCHEMBL4417489 | 0.74 | MAPT (0.40) | HDAC1HDAC6ACHEMAPTKMT2A | |
| SCHEMBL19203396 | 0.72 | HDAC1 (0.37) | HDAC1HDAC6ACHEMAPTKMT2A | |
| SCHEMBL901110 | 0.69 | SMN1; SMN2 (0.49) | HDAC1HDAC6ACHEMAPTALDH1A1 | |
| SCHEMBL20408990 | 0.69 | KMT2A (0.40) | HDAC1HDAC6ACHEMAPTKMT2A | |
| SCHEMBL13438977 | 0.68 | HDAC1 (0.34) | HDAC1HDAC6ACHEMAPTNISCH | |
| SCHEMBL15075247 | 0.68 | MAOA (0.43) | HDAC1HDAC6ACHEMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3548475-B1 | SULFONAMIDE ANALOGUES OF GALIELLALACTONE | GLACTONE PHARMA DEV AB (SE) | 2021-03-03 | — | — | EP | disclosed |