Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23048665 | 0.73 | HRH4 (0.52) | KDM4E | |
| SCHEMBL23048624 | 0.68 | DYRK1A (0.39) | — | |
| SCHEMBL23048862 | 0.65 | HRH3 (0.40) | — | |
| SCHEMBL23048742 | 0.62 | PIK3CA (0.38) | KDM4EADRB1PIK3CA | |
| SCHEMBL29886325 | 0.59 | ALDH1A3 (0.49) | KDM4EADRB1PIK3CA | |
| SCHEMBL19547082 | 0.58 | HRH4 (0.54) | ADRB1PIK3CA | |
| SCHEMBL23916232 | 0.57 | HRH4 (0.39) | KDM4EADRB1PIK3CA | |
| SCHEMBL23916158 | 0.55 | HRH4 (0.54) | KDM4E | |
| SCHEMBL23916096 | 0.55 | HRH4 (0.54) | KDM4E | |
| SCHEMBL27827453 | 0.55 | HRH4 (0.54) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3448386-B1 | ISOQUINOLIN-3-YL CARBOXAMIDES AND PREPARATION AND USE THEREOF | SAMUMED LLC (US) | 2021-03-03 | — | — | EP | disclosed |