SCHEMBL23051151

SCHEMBL23051151

O=C(Cn1cnnn1)N[C@@H]1C(=O)N2C(C(=O)O)=C(CSc3ccccc3)CSC12

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 4/20 0.73
▸ SLC22A6 Q4U2R8 2/20 0.73
▸ SLC22A8 Q8TCC7 2/20 0.73
▸ SLC22A11 Q9NSA0 2/20 0.73
▸ PTGS2 P35354 1/20 0.73
▸ MAPT P10636 7/20 0.62
▸ TDP1 Q9NUW8 7/20 0.62
▸ HSD17B10 Q99714 2/20 0.62
▸ ABCC4 O15439 1/20 0.62
▸ BLM P54132 1/20 0.62
▸ CYP3A4 P08684 1/20 0.62
▸ NFKB1 P19838 1/20 0.62
▸ KDM4E B2RXH2 1/20 0.58
▸ MEN1 O00255 1/20 0.58
▸ KMT2A Q03164 1/20 0.58
▸ POLB P06746 6/20 0.56
▸ NR1I2 O75469 1/20 0.54
▸ PGR P06401 1/20 0.54
▸ PPARG P37231 1/20 0.54
▸ CA5A P35218 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11190435 1.00 LMNA (0.73) LMNASLC22A6SLC22A8SLC22A11PTGS2
SCHEMBL11190440 1.00 LMNA (0.73) LMNASLC22A6SLC22A8SLC22A11PTGS2
SCHEMBL25938280 0.88 LMNA (0.58) LMNASLC22A6SLC22A8SLC22A11PTGS2
Ceftezole SCHEMBL147529 0.87 LMNA (0.79) LMNASLC22A6SLC22A8SLC22A11PTGS2
Ceftezole SCHEMBL11033790 0.87 LMNA (0.79) LMNASLC22A6SLC22A8SLC22A11PTGS2
Ceftezole SCHEMBL11033793 0.87 LMNA (0.79) LMNASLC22A6SLC22A8SLC22A11PTGS2
SCHEMBL11346639 0.86 LMNA (0.73) LMNASLC22A6SLC22A8SLC22A11PTGS2
Ceftezole SCHEMBL2259026 0.86 LMNA (0.78) LMNASLC22A6SLC22A8SLC22A11PTGS2
Cefazolin SCHEMBL11031717 0.85 LMNA (1.00) LMNASLC22A6SLC22A8SLC22A11PTGS2
Cefazolin SCHEMBL16072809 0.85 LMNA (1.00) LMNASLC22A6SLC22A8SLC22A11PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119096144-A Rapid diagnostic test for antibiotic resistance and methods of use and preparation thereof 拜奥普诊断公司 2024-12-06 — — CN disclosed
EP-4469800-A1 RAPID DIAGNOSTIC TEST FOR ANTIBIOTIC RESISTANCE, AND METHODS OF USE AND METHODS OF MAKING THEREOF Bioamp Diagnostics, Inc. (US) 2024-12-04 — — EP disclosed
WO-2023147071-A9 RAPID DIAGNOSTIC TEST FOR ANTIBIOTIC RESISTANCE, AND METHODS OF USE AND METHODS OF MAKING THEREOF BIOAMP DIAGNOSTICS, INC. (US) 2024-07-11 — — WO disclosed
WO-2023147071-A9 RAPID DIAGNOSTIC TEST FOR ANTIBIOTIC RESISTANCE, AND METHODS OF USE AND METHODS OF MAKING THEREOF BIOAMP DIAGNOSTICS, INC. (US) 2024-07-11 — — WO disclosed
WO-2023147071-A1 RAPID DIAGNOSTIC TEST FOR ANTIBIOTIC RESISTANCE, AND METHODS OF USE AND METHODS OF MAKING THEREOF BIOAMP DIAGNOSTICS, INC. (US) 2023-08-03 — — WO disclosed
WO-2023147071-A1 RAPID DIAGNOSTIC TEST FOR ANTIBIOTIC RESISTANCE, AND METHODS OF USE AND METHODS OF MAKING THEREOF BIOAMP DIAGNOSTICS, INC. (US) 2023-08-03 — — WO disclosed
US-20220177947-A1 Compounds to Identify Beta-Lactamases, and Methods of Use Thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-06-09 — — US disclosed
WO-2021041583-A1 COMPOUNDS TO IDENTIFY BETA-LACTAMASES, AND METHODS OF USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-03-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220177947-A1 Compounds to Identify Beta-Lactamases, and Methods of Use Thereof GUSB, GLB1, MGAM LMNA 403/4885SLC22A6 1406/4885SLC22A8 1391/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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