Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | XDH | P47989 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23052349 | 0.82 | POLB (0.66) | KMT2ALMNAALDH1A1XDHKDM4E | |
| SCHEMBL14133478 | 0.81 | PKM (0.75) | KMT2ALMNAMEN1NPSR1ALDH1A1 | |
| SCHEMBL23052458 | 0.68 | ALDH1A1 (0.80) | ALDH1A1XDH | |
| SCHEMBL23268895 | 0.68 | ALDH1A1 (0.64) | KMT2AMEN1ALDH1A1XDH | |
| SCHEMBL14540778 | 0.68 | ALDH1A1 (0.56) | ALDH1A1XDHMAOAMAOB | |
| SCHEMBL18651478 | 0.68 | MAOA (0.68) | KMT2ALMNAMEN1NPSR1ALDH1A1 | |
| SCHEMBL23052332 | 0.67 | KMT2A (0.73) | KMT2ALMNAMEN1NPSR1ALDH1A1 | |
| SCHEMBL14540721 | 0.67 | ALDH1A1 (0.66) | KMT2ALMNAMEN1NPSR1ALDH1A1 | |
| SCHEMBL14540722 | 0.67 | ALDH1A1 (0.55) | ALDH1A1XDHMAOAMAOB | |
| SCHEMBL20989162 | 0.67 | KMT2A (0.78) | KMT2ALMNAMEN1NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021039824-A1 | RNA METHYLTRANSFERASE INHIBITOR, SCREENING METHOD THEREFOR, ANTI-CANCER AGENT EFFICACY ASSESSMENT MARKER, AND KIT FOR EFFECTIVELY PREDICTING FTSJ1 INHIBITOR | 国立大学法人 岡山大学 | 2021-03-04 | — | — | WO | disclosed |