Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.71 |
| ▸ | RAB9A | P51151 | 2/20 | 0.71 |
| ▸ | MAOB | P27338 | 3/20 | 0.70 |
| ▸ | MAOA | P21397 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.67 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.67 |
| ▸ | EGFR | P00533 | 3/20 | 0.66 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.65 |
| ▸ | TERT | O14746 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23052465 | 1.00 | NPC1 (0.71) | NPC1RAB9AMAOBMAOAMEN1 | |
| SCHEMBL23052463 | 0.91 | CA1 (0.74) | MAOBMAOAABCB1ABCG2EGFR | |
| SCHEMBL28260652 | 0.91 | CA1 (0.62) | NPC1RAB9AMAOBMAOAABCB1 | |
| SCHEMBL28260637 | 0.90 | CA1 (0.61) | NPC1RAB9AMAOBMAOAMEN1 | |
| SCHEMBL21440072 | 0.89 | MAOB (0.81) | NPC1RAB9AMAOBMAOAMEN1 | |
| SCHEMBL15436205 | 0.89 | MAOB (0.81) | NPC1RAB9AMAOBMAOAMEN1 | |
| SCHEMBL23052467 | 0.89 | MAOB (0.71) | MAOBMAOAKMT2AABCB1ABCG2 | |
| SCHEMBL28736399 | 0.87 | MAOA (0.62) | NPC1RAB9AMAOBMAOA | |
| SCHEMBL28736288 | 0.84 | CA1 (0.55) | NPC1RAB9AMAOA | |
| SCHEMBL14133236 | 0.84 | PTGS2 (0.64) | MAOBABCB1ABCG2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021039824-A1 | RNA METHYLTRANSFERASE INHIBITOR, SCREENING METHOD THEREFOR, ANTI-CANCER AGENT EFFICACY ASSESSMENT MARKER, AND KIT FOR EFFECTIVELY PREDICTING FTSJ1 INHIBITOR | 国立大学法人 岡山大学 | 2021-03-04 | — | — | WO | disclosed |