Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23054307 | 0.95 | ALDH1A1 (0.58) | ALDH1A1LMNAHTTSMN1; SMN2MAPK1 | |
| SCHEMBL14299193 | 0.88 | CA1 (0.64) | ALDH1A1LMNAHTTSMN1; SMN2MEN1 | |
| SCHEMBL23052429 | 0.88 | LMNA (0.51) | ALDH1A1LMNAHTTSMN1; SMN2MAPK1 | |
| SCHEMBL31014206 | 0.86 | CA1 (0.57) | ALDH1A1LMNAHTTSMN1; SMN2MAPK1 | |
| SCHEMBL635208 | 0.81 | ALDH1A1 (0.70) | ALDH1A1LMNAHTTMAPK1PKM | |
| SCHEMBL6498413 | 0.81 | ALDH1A1 (0.63) | ALDH1A1LMNAHTTSMN1; SMN2MEN1 | |
| SCHEMBL16508871 | 0.81 | CA1 (0.59) | ALDH1A1LMNAHTTSMN1; SMN2PKM | |
| SCHEMBL29208967 | 0.80 | ALDH1A1 (0.53) | ALDH1A1LMNAHTTSMN1; SMN2PKM | |
| SCHEMBL7103280 | 0.80 | ALDH1A1 (0.72) | ALDH1A1LMNAHTTSMN1; SMN2MAPK1 | |
| SCHEMBL7130425 | 0.80 | ALDH1A1 (0.60) | ALDH1A1LMNAHTTSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021039824-A1 | RNA METHYLTRANSFERASE INHIBITOR, SCREENING METHOD THEREFOR, ANTI-CANCER AGENT EFFICACY ASSESSMENT MARKER, AND KIT FOR EFFECTIVELY PREDICTING FTSJ1 INHIBITOR | 国立大学法人 岡山大学 | 2021-03-04 | — | — | WO | disclosed |