Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | PKM | P14618 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | XDH | P47989 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3314961 | 0.76 | XBP1 (0.60) | KDM4EPKMPOLB | |
| SCHEMBL3314444 | 0.74 | PKM (0.55) | KDM4EPKMPOLBMAPT | |
| SCHEMBL3311133 | 0.74 | MAOB (0.58) | KDM4EPKMMAPT | |
| SCHEMBL3312487 | 0.74 | KDM4E (0.64) | KDM4EPKMP2RY6MAPT | |
| SCHEMBL24767745 | 0.74 | P2RY6 (1.00) | KDM4EPKMPOLBRXFP1P2RY6 | |
| SCHEMBL24768795 | 0.72 | P2RY6 (0.85) | KDM4EPKMPOLBRXFP1P2RY6 | |
| SCHEMBL3316509 | 0.72 | XBP1 (0.76) | KDM4EPKMPOLBRXFP1P2RY6 | |
| SCHEMBL3312926 | 0.72 | XBP1 (0.76) | KDM4EPKMPOLBRXFP1MAPT | |
| SCHEMBL3310763 | 0.70 | PKM (0.57) | KDM4EPKMP2RY6 | |
| SCHEMBL23052416 | 0.69 | LMNA (0.58) | KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021039824-A1 | RNA METHYLTRANSFERASE INHIBITOR, SCREENING METHOD THEREFOR, ANTI-CANCER AGENT EFFICACY ASSESSMENT MARKER, AND KIT FOR EFFECTIVELY PREDICTING FTSJ1 INHIBITOR | 国立大学法人 岡山大学 | 2021-03-04 | — | — | WO | disclosed |