Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.81 |
| ▸ | PKM | P14618 | 2/20 | 0.81 |
| ▸ | LMNA | P02545 | 3/20 | 0.73 |
| ▸ | POLB | P06746 | 3/20 | 0.66 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | RXRB | P28702 | 1/20 | 0.51 |
| ▸ | RXRG | P48443 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24768795 | 0.92 | P2RY6 (0.85) | P2RY6KDM4EPKMLMNAPOLB | |
| SCHEMBL23499879 | 0.78 | POLB (0.70) | P2RY6KDM4EPKMLMNAPOLB | |
| SCHEMBL29878408 | 0.78 | POLB (0.70) | P2RY6KDM4EPKMLMNAPOLB | |
| SCHEMBL22420543 | 0.77 | POLB (0.88) | P2RY6KDM4EPKMLMNAPOLB | |
| SCHEMBL14659215 | 0.76 | POLB (0.69) | P2RY6KDM4EPKMLMNAPOLB | |
| SCHEMBL22420636 | 0.75 | PKM (0.76) | P2RY6KDM4EPKMLMNAPOLB | |
| SCHEMBL23052343 | 0.74 | KDM4E (0.74) | P2RY6KDM4EPKMPOLBRXFP1 | |
| SCHEMBL29878869 | 0.74 | POLB (0.63) | P2RY6KDM4EPKMLMNAPOLB | |
| SCHEMBL23499852 | 0.74 | POLB (0.63) | P2RY6KDM4EPKMLMNAPOLB | |
| SCHEMBL22420542 | 0.73 | PKM (0.74) | P2RY6KDM4EPKMLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022252391-A1 | APPLICATION OF PYRAZOLE DERIVATIVE IN PREPARATION OF P2Y6R RELATED MEDICINES FOR TREATING ATHEROSCLEROSIS AND RESISTING INFLAMMATION | 苏州大学 | 2022-12-08 | — | — | WO | disclosed |