Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.72 |
| ▸ | MAPT | P10636 | 3/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.72 |
| ▸ | HPGD | P15428 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.53 |
| ▸ | TOP2A | P11388 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | EDNRB | P24530 | 7/20 | 0.43 |
| ▸ | EDNRA | P25101 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25943638 | 0.90 | KDM4E (0.58) | ALDH1A1KDM4EMAPTNPSR1HPGD | |
| SCHEMBL23053117 | 0.90 | KDM4E (0.76) | ALDH1A1KDM4EMAPTNPSR1HPGD | |
| SCHEMBL11954030 | 0.90 | ALDH1A1 (0.75) | ALDH1A1KDM4EMAPTNPSR1HPGD | |
| SCHEMBL25944371 | 0.90 | ALDH1A1 (0.70) | ALDH1A1KDM4EMAPTNPSR1HPGD | |
| SCHEMBL23053119 | 0.89 | ALDH1A1 (0.75) | ALDH1A1KDM4EMAPTNPSR1HPGD | |
| SCHEMBL23053193 | 0.88 | ALDH1A1 (0.72) | ALDH1A1KDM4EMAPTNPSR1HPGD | |
| SCHEMBL23053107 | 0.86 | ALDH1A1 (0.75) | ALDH1A1KDM4EMAPTNPSR1HPGD | |
| SCHEMBL21383473 | 0.85 | KDM4E (0.61) | ALDH1A1KDM4EMAPTNPSR1HPGD | |
| Justicidin A SCHEMBL168356 | 0.85 | ALDH1A1 (0.82) | ALDH1A1KDM4EMAPTNPSR1HPGD | |
| Justicidin A SCHEMBL29731045 | 0.85 | ALDH1A1 (0.82) | ALDH1A1KDM4EMAPTNPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230248754-A1 | Patentiflorin A Analogs as Antiviral Agents | HONG KONG BAPTIST UNIVERSITY (CN) | 2023-08-10 | — | — | US | disclosed |
| US-11638713-B2 | Patentiflorin A analogs as antiviral agents | HONG KONG BAPTIST UNIVERSITY (CN) | 2023-05-02 | — | — | US | disclosed |
| US-20210060042-A1 | Patentiflorin A Analogs as Antiviral Agents | HONG KONG BAPTIST UNIVERSITY (HK) | 2021-03-04 | — | — | US | disclosed |
| WO-2021037077-A1 | PATENTIFLORIN A ANALOGS AS ANTIVIRAL AGENTS | HONG KONG BAPTIST UNIVERSITY (CN) | 2021-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230248754-A1 | Patentiflorin A Analogs as Antiviral Agents | MAVS, MIF, SARS1 | ALDH1A1 2987/4885KDM4E 4386/4885MAPT 2419/4885 |
| US-11638713-B2 | Patentiflorin A analogs as antiviral agents | MAVS, MIF, SARS1 | ALDH1A1 2987/4885KDM4E 4386/4885MAPT 2419/4885 |
| US-20210060042-A1 | Patentiflorin A Analogs as Antiviral Agents | MAVS, MIF, SARS1 | ALDH1A1 2987/4885KDM4E 4386/4885MAPT 2419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.