Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4A3 | P38919 | 2/20 | 0.46 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.44 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.44 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.44 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.44 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.44 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SPR | P35270 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 2/20 | 0.38 |
| ▸ | MGAM | O43451 | 4/20 | 0.37 |
| ▸ | SI | P14410 | 4/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27836233 | 0.84 | EIF4A3 (0.48) | EIF4A3PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL888682 | 0.81 | KIF11 (0.49) | EIF4A3PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL25786727 | 0.75 | AURKA (0.46) | EIF4A3PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL1558774 | 0.75 | PRKAB2 (0.51) | EIF4A3PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL719008 | 0.74 | MAPT (0.57) | NOD2GAAKDM4EMGAMSI | |
| SCHEMBL19178970 | 0.72 | TDO2 (0.63) | EIF4A3PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL18973668 | 0.71 | MEN1 (0.45) | EIF4A3PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL10147746 | 0.71 | KIF11 (0.49) | EIF4A3PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL3723653 | 0.71 | PRKAB2 (0.47) | EIF4A3PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL21008475 | 0.70 | HTR1D (0.53) | EIF4A3KIF11HTR1DMAPTHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021038095-A1 | PEPTIDES AND METHODS FOR THE CARBON-CARBON BOND FORMATION | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2021-03-04 | — | — | WO | disclosed |