Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 1/20 | 0.49 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.36 |
| ▸ | GNPAT | O15228 | 2/20 | 0.34 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | NMT2 | O60551 | 1/20 | 0.32 |
| ▸ | NMT1 | P30419 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 2/20 | 0.30 |
| ▸ | MMP3 | P08254 | 2/20 | 0.30 |
| ▸ | MMP9 | P14780 | 2/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21626605 | 1.00 | KISS1R (0.49) | KISS1RSIRT5GNPATSIRT6SIRT1 | |
| SCHEMBL24155382 | 0.93 | KISS1R (0.45) | KISS1RSIRT5GNPATSIRT6SIRT1 | |
| SCHEMBL24155383 | 0.93 | KISS1R (0.45) | KISS1RSIRT5GNPATSIRT6SIRT1 | |
| SCHEMBL24155380 | 0.93 | KISS1R (0.45) | KISS1RSIRT5GNPATSIRT6SIRT1 | |
| SCHEMBL16221913 | 0.93 | KISS1R (0.45) | KISS1RSIRT5GNPATSIRT6SIRT1 | |
| SCHEMBL19035531 | 0.87 | SIRT6 (0.45) | KISS1RSIRT5SIRT6SIRT1MMP1 | |
| SCHEMBL18291772 | 0.87 | SIRT6 (0.45) | KISS1RSIRT5SIRT6SIRT1NMT2 | |
| SCHEMBL24155387 | 0.86 | KISS1R (0.40) | KISS1RSIRT5GNPATSIRT6SIRT1 | |
| SCHEMBL13366903 | 0.85 | KISS1R (0.53) | KISS1RCACNA1BHTR2AHRH1 | |
| SCHEMBL14525182 | 0.85 | KISS1R (0.53) | KISS1RCACNA1BHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021035310-A1 | TARGETED DENDRIMER CONJUGATES | STARPHARMA PTY LTD (AU) | 2021-03-04 | — | — | WO | disclosed |